IR@PKUHSC  > 北京大学口腔医学院
学科主题口腔医学
Beneficial Effects and Safety of Corticosteroids Combined with Traditional Chinese Medicine for Pemphigus: A Systematic Review
Zhou, Tingting; Zhou, Peiru; Hua, Hong; Liu, Xiaosong
刊名EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
2015
DOI10.1155/2015/815358
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Integrative & Complementary Medicine
研究领域[WOS]Integrative & Complementary Medicine
英文摘要

Objective. To evaluate the beneficial effects and safety of corticosteroids combined with traditional Chinese medicine (TCM) for pemphigus. Methods. Seven electronic databases were searched to identify any potential randomized controlled trials (RCTs) or clinical controlled trials (CCTs) that compared corticosteroids with and without TCM for the treatment of pemphigus, published in any language. Remission of the mucocutaneous lesions, therapeutic duration, dosage of corticosteroids, and specific antibody titers were employed as the main outcome measures. The methodological quality of the included studies was assessed using the Cochrane Handbook for Systematic Review of Interventions and Rev Man 5.1.0 software. Results. Four RCTs with a total of 199 patients were included in the present review. Management with corticosteroids combined with TCM seemed to benefit pemphigus patients in terms of healing of lesions, prevention of complications and relapse, and reduced interferon-gamma (IFN-gamma) level. The trials were not of high methodological quality. No study mentioned allocation concealment and blinding. Only one trial reported adverse events, and it indicated that the safety of corticosteroids combined with TCM was uncertain. Conclusion. There is some, albeit weak, evidence to show that combined treatment with corticosteroids with TCM could be of benefit for some patients with pemphigus. The efficacy and safety of this combined treatment should be evaluated further in better designed, fully powered, and confirmatory RCTs.

语种英语
WOS记录号WOS:000352460100001
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67029
专题北京大学口腔医学院
北京大学口腔医学院_口腔黏膜科
作者单位Peking Univ, Sch & Hosp Stomatol, Dept Oral Med, Beijing 100081, Peoples R China
推荐引用方式
GB/T 7714
Zhou, Tingting,Zhou, Peiru,Hua, Hong,et al. Beneficial Effects and Safety of Corticosteroids Combined with Traditional Chinese Medicine for Pemphigus: A Systematic Review[J]. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,2015.
APA Zhou, Tingting,Zhou, Peiru,Hua, Hong,&Liu, Xiaosong.(2015).Beneficial Effects and Safety of Corticosteroids Combined with Traditional Chinese Medicine for Pemphigus: A Systematic Review.EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE.
MLA Zhou, Tingting,et al."Beneficial Effects and Safety of Corticosteroids Combined with Traditional Chinese Medicine for Pemphigus: A Systematic Review".EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2015).
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