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学科主题: 临床医学
题名:
Accommodation-induced intraocular pressure changes in progressing myopes and emmetropes
作者: Yan, L.; Huibin, L.; Xuemin, L.
刊名: EYE
发表日期: 2014-11-01
DOI: 10.1038/eye.2014.208
卷: 28, 期:11, 页:1334-1340
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Ophthalmology
研究领域[WOS]: Ophthalmology
关键词[WOS]: GOLDMANN APPLANATION TONOMETER ; CENTRAL CORNEAL THICKNESS ; OCULAR-RESPONSE-ANALYZER ; AXIAL LENGTH ; REBOUND TONOMETRY ; REFRACTIVE ERROR ; ICARE TONOMETER ; EYE GROWTH ; CHILDREN ; IOP
英文摘要:

Purpose To investigate the changes of intraocular pressure (IOP) and anterior eye segment biometric parameters under different accommodative statuses in progressing myopes and emmetropes.

Methods Forty-six progressing myopes and 40 emmetropes participated in this study. All the subjects had their IOP and anterior eye segment biometric parameters (including corneal thickness, anterior chamber depth, anterior chamber angle width, and lens thickness) measured using iCare rebound tonometer and VisanteTM anterior segment-optical coherence tomography while accommodative stimuli of 0, 3, and 6D were presented.

Results There was no significant difference in IOP between progressing myopes and emmetropes when no accommodation was induced (16.22 +/- 4.11 vs 17.01 +/- 3.72, respectively, t = -0.93, P > 0.05). However, IOP significantly increased with accommodation in progressing myopes (mean change +1.02 +/- 2.07 mmHg from 0D to 6D, F = 5.35, P < 0.01), but remained unchanged (mean change -0.76 +/- 3.22 mmHg from 0D to 6D, F = 1.46, P > 0.05) in emmetropes. Meanwhile, we found that their anterior chamber depth decreased (P < 0.01), anterior chamber angle narrowed (P <0.01), and lens thickened (P < 0.01) significantly with accommodation, both in progressing myopes and emmetropes.

Conclusions Although no difference was detected between the IOPs of progressing myopes and emmetropes without accommodation, accommodation could induce transient IOP elevation in progressing myopes. Simultaneously, we found that their anterior chamber depth decreased, anterior chamber angle narrowed, and lens thickened with accommodation. Although emmetropes showed the similar anterior eye segment structure changes, their IOPs did not increase with accommodation. Our study indicated that IOP elevation with accommodation in progressing myopes might be related to myopia progression.

语种: 英语
WOS记录号: WOS:000345428900011
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67042
Appears in Collections:北京大学第三临床医学院_眼科_期刊论文

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作者单位: Peking Univ, Hosp 3, Dept Ophthalmol, Beijing 100191, Peoples R China

Recommended Citation:
Yan, L.,Huibin, L.,Xuemin, L.. Accommodation-induced intraocular pressure changes in progressing myopes and emmetropes[J]. EYE,2014,28(11):1334-1340.
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