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学科主题临床医学
Accommodation-induced intraocular pressure changes in progressing myopes and emmetropes
Yan, L.; Huibin, L.; Xuemin, L.
刊名EYE
2014-11-01
DOI10.1038/eye.2014.208
28期:11页:1334-1340
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Ophthalmology
研究领域[WOS]Ophthalmology
关键词[WOS]GOLDMANN APPLANATION TONOMETER ; CENTRAL CORNEAL THICKNESS ; OCULAR-RESPONSE-ANALYZER ; AXIAL LENGTH ; REBOUND TONOMETRY ; REFRACTIVE ERROR ; ICARE TONOMETER ; EYE GROWTH ; CHILDREN ; IOP
英文摘要

Purpose To investigate the changes of intraocular pressure (IOP) and anterior eye segment biometric parameters under different accommodative statuses in progressing myopes and emmetropes.

Methods Forty-six progressing myopes and 40 emmetropes participated in this study. All the subjects had their IOP and anterior eye segment biometric parameters (including corneal thickness, anterior chamber depth, anterior chamber angle width, and lens thickness) measured using iCare rebound tonometer and VisanteTM anterior segment-optical coherence tomography while accommodative stimuli of 0, 3, and 6D were presented.

Results There was no significant difference in IOP between progressing myopes and emmetropes when no accommodation was induced (16.22 +/- 4.11 vs 17.01 +/- 3.72, respectively, t = -0.93, P > 0.05). However, IOP significantly increased with accommodation in progressing myopes (mean change +1.02 +/- 2.07 mmHg from 0D to 6D, F = 5.35, P < 0.01), but remained unchanged (mean change -0.76 +/- 3.22 mmHg from 0D to 6D, F = 1.46, P > 0.05) in emmetropes. Meanwhile, we found that their anterior chamber depth decreased (P < 0.01), anterior chamber angle narrowed (P <0.01), and lens thickened (P < 0.01) significantly with accommodation, both in progressing myopes and emmetropes.

Conclusions Although no difference was detected between the IOPs of progressing myopes and emmetropes without accommodation, accommodation could induce transient IOP elevation in progressing myopes. Simultaneously, we found that their anterior chamber depth decreased, anterior chamber angle narrowed, and lens thickened with accommodation. Although emmetropes showed the similar anterior eye segment structure changes, their IOPs did not increase with accommodation. Our study indicated that IOP elevation with accommodation in progressing myopes might be related to myopia progression.

语种英语
WOS记录号WOS:000345428900011
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67042
专题北京大学第三临床医学院_眼科
作者单位Peking Univ, Hosp 3, Dept Ophthalmol, Beijing 100191, Peoples R China
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GB/T 7714
Yan, L.,Huibin, L.,Xuemin, L.. Accommodation-induced intraocular pressure changes in progressing myopes and emmetropes[J]. EYE,2014,28(11):1334-1340.
APA Yan, L.,Huibin, L.,&Xuemin, L..(2014).Accommodation-induced intraocular pressure changes in progressing myopes and emmetropes.EYE,28(11),1334-1340.
MLA Yan, L.,et al."Accommodation-induced intraocular pressure changes in progressing myopes and emmetropes".EYE 28.11(2014):1334-1340.
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