IR@PKUHSC  > 北京大学第二临床医学院
学科主题临床医学
Effect of Chinese Drugs for Supplementing Qi, Nourishing Yin and Activating Blood Circulation on Myocardial Perfusion in Patients with Acute Myocardial Infarction after Revascularization
Li Yong-qiang1; Jin Mei2; Qiu Sheng-lei2; Wang Pei-li1; Zhu Tian-gang3; Wang Cheng-long1; Li Tian-chang4; Liu Hong-xu2; Bian Hong4; Yao Li-fang1; Shi Da-zhuo1
关键词Chinese drugs for supplementing qi nourishing yin and activating blood circulation acute myocardial infarction blood circulation rebuilding myocardial perfusion Doppler&prime s ultrasonic acoustic photography
刊名CHINESE JOURNAL OF INTEGRATIVE MEDICINE
2009-02-01
DOI10.1007/s11655-009-0019-7
15期:1页:19-25
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Integrative & Complementary Medicine
研究领域[WOS]Integrative & Complementary Medicine
关键词[WOS]PERCUTANEOUS CORONARY INTERVENTION ; NO-REFLOW
英文摘要

Objective: To observe the effects of Chinese drugs for supplementing qi, nourishing yin and activating blood circulation on the myocardial perfusion in acute myocardial infarction (AMI) patients after revascularization. Methods: Eighty patients with anterior or inferior ventricular wall AMI, who had received revascularization by intravenous thrombolysis or coronary bypass, were randomized into the treated group and the control group equally, both treated with conventional Western medical treatment, but combined, respectively, with Xinyue Capsule (sic, XYC) plus Composite Salvia Tablet (CST) and placebo for 3 months. Dobutamine stress echocardiography (DSE) was performed 14 days and 3 months after revascularization, respectively on every patient to observe blood perfusion extent (b value), myocardial perfusion velocity (k value) and local blood flow volume (k x b) in left ventricular infarction-related vascular segments under stressed state. Results: With 5 cases dropping out in the observation period (3 in the treated group and 2 in the control group), the trial was completed in 75 patients in total. The 14-day DSE shows that the b value and k x b value of left anterior ventricular wall mid segment and apex segment, and the k value of apex segment in patients with anterior wall AMI, as well as the b value and k x b of basal segment in patients with inferior wall AMI in the treated group were significantly higher than those in the control group (P<0.05 or P<0.01). The 3-month DSE shows that the b value of apex segment, k x b value of basal segment, mid segment and apex segment of left anterior ventricular wall in patients with anterior wall AMI as well as the b value and k x b value of basal segment of left inferior ventricular wall in patients with inferior wall AMI were all higher in the treated group than those in the control group, respectively (P<0.05). The comparison between 14-day DSE and 3-month DSE in the treated group showed that the b value of apex segment of left anterior ventricular wall in patients with anterior wall AMI and the k x b value of apex segment and mid segment of left inferior ventricular wall in patients with inferior wall AMI significantly increased along with the on-going treatment (P<0.05). Conclusion: Therapy with Chinese drugs for supplementing qi, nourishing yin and activating blood circulation in combination with conventional Western medical treatment could obviously improve the blood perfusion at the myocardial tissue level in infarction-related vascular segments.

语种英语
WOS记录号WOS:000263217400005
引用统计
被引频次:10[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67082
专题北京大学第二临床医学院
北京大学第二临床医学院_心血管内科
作者单位1.China Acad Chinese Med Sci, Xiyuan Hosp, Ctr Cardiovasc, Beijing 100091, Peoples R China
2.Capital Med Univ, Beijing Hosp Tradit Chinese Med, Dept Internal Cardiac Med, Beijing 100010, Peoples R China
3.Peking Univ, Peoples Hosp, Dept Internal Cardiac Med, Beijing 100044, Peoples R China
4.Capital Med Univ, Tongren Hosp, Dept Internal Cardiac Med, Beijing 100730, Peoples R China
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GB/T 7714
Li Yong-qiang,Jin Mei,Qiu Sheng-lei,et al. Effect of Chinese Drugs for Supplementing Qi, Nourishing Yin and Activating Blood Circulation on Myocardial Perfusion in Patients with Acute Myocardial Infarction after Revascularization[J]. CHINESE JOURNAL OF INTEGRATIVE MEDICINE,2009,15(1):19-25.
APA Li Yong-qiang.,Jin Mei.,Qiu Sheng-lei.,Wang Pei-li.,Zhu Tian-gang.,...&Shi Da-zhuo.(2009).Effect of Chinese Drugs for Supplementing Qi, Nourishing Yin and Activating Blood Circulation on Myocardial Perfusion in Patients with Acute Myocardial Infarction after Revascularization.CHINESE JOURNAL OF INTEGRATIVE MEDICINE,15(1),19-25.
MLA Li Yong-qiang,et al."Effect of Chinese Drugs for Supplementing Qi, Nourishing Yin and Activating Blood Circulation on Myocardial Perfusion in Patients with Acute Myocardial Infarction after Revascularization".CHINESE JOURNAL OF INTEGRATIVE MEDICINE 15.1(2009):19-25.
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