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学科主题: 药学
题名:
Synthesis of 5-substituted-3-[(2 ′ R,4 ′ R)-4 ′-hydroxy-2 ′-hydroxymethyltetrahydrofuran-4 ′-yl]-1,2,4-oxadiazoles and their epimers
作者: Wu, WD; Ma, LT; Zhang, LH
关键词: nucleoside analogue ; 1,2,4-oxadiazole ; transacylation
刊名: CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
发表日期: 2001-11-01
卷: 17, 期:4, 页:407-414
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
英文摘要:

The syntheses of 5-substituted-3-[(2′ R, 4′ R)-4′ -hydroxy-2′ -hydroxymethyltetrahydrofuran-4′-yl]-1,2,4-oxadiazoles and their epimers were accomplished with the aid of the construction of 1, 2, 4-oxadiazoles by condensation of O-acylated cyanohydrins with hydroxylamine via intramolecular transacylation and subsequent cyclization.

语种: 英语
WOS记录号: WOS:000172664000011
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67100
Appears in Collections:北京大学药学院_期刊论文

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作者单位: Peking Univ, Sch Pharmaceut Sci, Natl Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China

Recommended Citation:
Wu, WD,Ma, LT,Zhang, LH. Synthesis of 5-substituted-3-[(2 ′ R,4 ′ R)-4 ′-hydroxy-2 ′-hydroxymethyltetrahydrofuran-4 ′-yl]-1,2,4-oxadiazoles and their epimers[J]. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,2001,17(4):407-414.
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