IR@PKUHSC  > 北京大学第二临床医学院
学科主题临床医学
The biocompatibility research of functional Schwann Cells induced from bone mesenchymal cells with chitosan conduit membrane
Zhang, PX; Xu, HL; Zhang, DY; Fu, ZG; Zhang, HB; Jiang, BG
关键词bone mesenchymal cells differentiation Schwann Cell
刊名ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY
2006
DOI10.1080/10731190500430198
34期:1页:91-99
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biotechnology & Applied Microbiology ; Engineering, Biomedical ; Materials Science, Biomaterials
研究领域[WOS]Biotechnology & Applied Microbiology ; Engineering ; Materials Science
关键词[WOS]MARROW STROMAL CELLS ; STEM-CELLS ; NERVE REGENERATION ; DIFFERENTIATION
英文摘要

To explore the adhesion and proliferation characteristics of bone marrow mesenchymal cells (MSCs) to chitosan conduit membrane, MSCs were induced by a sequential composition Beta-mercaptoethanol, retinoic acid, forskolin, basic-FGF, PDGF and heregulin. Schwann Cell markers, namely S-100 and GFAP, were used to discriminate the induced MSCs′ properties by immunofluorescent staining. These results suggested that MSCs can take on Schwann cell′s phenotype in vitro and the induce MSCs were gifted with good biocompatibility to biogradable chitosan conduit membrane. The results provided the possibilities to using the induced MSCs with chitosan conduit membrane in artificial peripherial nerve fields to promote nerve regeneration.

语种英语
WOS记录号WOS:000234545400007
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67158
专题北京大学第二临床医学院
作者单位Peking Univ, Peoples Hosp, Dept Trauma & Orthopead, Beijing, Peoples R China
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GB/T 7714
Zhang, PX,Xu, HL,Zhang, DY,et al. The biocompatibility research of functional Schwann Cells induced from bone mesenchymal cells with chitosan conduit membrane[J]. ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY,2006,34(1):91-99.
APA Zhang, PX,Xu, HL,Zhang, DY,Fu, ZG,Zhang, HB,&Jiang, BG.(2006).The biocompatibility research of functional Schwann Cells induced from bone mesenchymal cells with chitosan conduit membrane.ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY,34(1),91-99.
MLA Zhang, PX,et al."The biocompatibility research of functional Schwann Cells induced from bone mesenchymal cells with chitosan conduit membrane".ARTIFICIAL CELLS BLOOD SUBSTITUTES AND BIOTECHNOLOGY 34.1(2006):91-99.
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