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学科主题: 精神卫生
题名:
Evaluation of Mood Disorder Questionnaire (MDQ) in Patients with Mood Disorders: A Multicenter Trial across China
作者: Yang, Hai-Chen1; Liu, Tie-Bang1; Rong, Han1; Bi, Jian-Qiang1; Ji, Er-Ni1; Peng, Hong-Jun2; Wang, Xiao-Ping2; Fang, Yi-Ru3; Yuan, Cheng-Mei3; Si, Tian-Mei4; Lu, Zheng5; Hu, Jian6; Chen, Zhi-Yu7; Huang, Yi8; Sun, Jing9; Li, Hui-Chun10; Hu, Chen11; Zhang, Jin-Bei12; Li, Ling-Jiang2
刊名: PLOS ONE
发表日期: 2014-04-04
DOI: 10.1371/journal.pone.0091895
卷: 9, 期:4
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Multidisciplinary Sciences
研究领域[WOS]: Science & Technology - Other Topics
关键词[WOS]: SCREENING BIPOLAR DISORDERS ; HYPOMANIA CHECKLIST HCL-32 ; MAJOR DEPRESSION ; SPECTRUM DISORDER ; II-DISORDER ; VALIDATION ; VALIDITY ; VERSION ; PREVALENCE ; INSTRUMENT
英文摘要:

Background: The aim of this study was to test the ability of the Chinese version of the Mood Disorder Questionnaire (MDQ) to identify Bipolar Disorders (BD) in patients diagnosed with Major Depressive Disorder (MDD) or Unipolar Disorder (UD) in the clinical setting.

Methods: 1,487 being treated for MDD or UD at 12 mental health centers across China, completed the MDQ and subsequently examined by the Mini International Neuropsychiatric Interview (MINI). Receiver Operating Characteristic(ROC) curves were used to determine the ability of the MDQ to differentiate between BD (BD, BD-I and BD-II) and MDD or UD and patients with BD-I from patients with BD-II.

Results: Of the 1,487 patients, 309 (20.8%) satisfied the DSM-IV criteria for BD: 118 (7.9%) for BD-I and 191 (12.8%) for BD-II. When only part one of the MDQ was used, the best cutoff was 7 between BD and UD (sensitivity 0.66, specificity 0.88, positive predictive value 0.59, negative predictive value 0.91), 6 between BD-II and UD, and 10 between BD-I and BD-II. If all three parts of the MDQ were used, the MDQ could not distinguish between BD and UD at a cutoff of 7 (or 6), and the sensitivity was only 0.22 (or 0.24).

Conclusion: The Chinese version of the MDQ had good psychometric features in screening bipolar disorders from depressive patients with mood disorders when part two and part three of the MDQ were ignored.

语种: 英语
所属项目编号: 200602032
项目资助者: scientific and technological bureau of Shenzhen in China ; AstraZeneca China
WOS记录号: WOS:000334107500009
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67176
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
2.Hangzhou Seventh Peoples Hosp, Hangzhou, Zhejiang, Peoples R China
3.Shenzhen Mental Hlth Ctr, Div Mood Disorders, Shenzhen Key Lab Psychol Healthcare, Shenzhen, Guangdong, Peoples R China
4.Cent S Univ, Xiangya Hosp 2, Mental Hlth Inst, Changsha, Hunan, Peoples R China
5.Shanghai Jiao Tong Univ, Sch Med, Shanghai Mental Hlth Ctr, Div Mood Disorders, Shanghai 200030, Peoples R China
6.Tongji Univ, Sch Med, Shanghai Tongji Hosp, Shanghai 200092, Peoples R China
7.Harbin Med Univ, Hosp 1, Harbin, Heilongjiang, Peoples R China
8.Sichuan Univ, West China Hosp, Chengdu, Sichuan, Peoples R China
9.Nanjing Med Univ, Affiliated Brain Hosp, Nanjing, Jiangsu, Peoples R China
10.Zhejiang Univ, Coll Med, Affiliated Hosp 2, Hangzhou, Zhejiang, Peoples R China
11.Capital Med Univ, Beijing Anding Hosp, Mood Disorders Ctr, Beijing, Peoples R China
12.Sun Yat Sen Univ, Affiliated Hosp 3, Guangzhou, Guangdong, Peoples R China

Recommended Citation:
Yang, Hai-Chen,Liu, Tie-Bang,Rong, Han,et al. Evaluation of Mood Disorder Questionnaire (MDQ) in Patients with Mood Disorders: A Multicenter Trial across China[J]. PLOS ONE,2014,9(4).
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