北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学公共卫生学院  > 期刊论文
学科主题: 公共卫生
题名:
Levels and regional trends of persistent organochlorines and polybrominated diphenyl ethers in Asian breast milk demonstrate POPs signatures unique to individual countries
作者: Haraguchi, Koichi1; Koizumi, Akio2; Inoue, Kayoko2; Harada, Kouji H.2; Hitomi, Toshiaki2; Minata, Mutsuko2; Tanabe, Miyako2; Kato, Yoshihisa3; Nishimura, Eri1; Yamamoto, Yoshiaki4; Watanabe, Takao5; Takenaka, Katsunobu6; Uehara, Shigeki7; Yang, Hye-Ran8; Kim, Min-Young8; Moon, Chan-Seok9; Kim, Hae-Sook10; Wang, Peiyu11; Liu, Aiping11; Hung, Nguyen Ngoc12
关键词: Human milk ; DDTs ; Pesticides ; PCBs ; PBDEs ; Asia ; Exposure
刊名: ENVIRONMENT INTERNATIONAL
发表日期: 2009-10-01
DOI: 10.1016/j.envint.2009.06.003
卷: 35, 期:7, 页:1072-1079
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Environmental Sciences
研究领域[WOS]: Environmental Sciences & Ecology
关键词[WOS]: BROMINATED FLAME RETARDANTS ; DIBENZO-P-DIOXINS ; POLYCHLORINATED-BIPHENYLS ; YANGTZE-RIVER ; CONTINUOUS SURVEILLANCE ; ACCUMULATION KINETICS ; CONTAMINATION STATUS ; SURFACE SEDIMENTS ; ARCHIVED SAMPLES ; JAPANESE MOTHERS
英文摘要:

Human breast milk samples collected in 2007-2008 from four countries, Vietnam (Hanoi), China (Beijing), Korea (Seoul) and Japan (Sendai, Kyoto and Takayama), were analyzed for persistent organic pollutants (POPS) such as dichlorodiphenyltrichloroethane and its metabolites (DDTs), chlordane-related compounds (CHLs), hexachlorocyclohexanes (HCHs), hexachlorobenzene (HCB), polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs). Comparing with previous surveys, the present study indicates that the DDTs in breast milk from China and Vietnam had gradually decreased during the last decade, but were still 5-10 times higher than those in other nations. The ratios of p,p′-DDE/p,p′-DDT and o,p′-DDT/p,p′-DDT were higher in Beijing than in the other countries, suggesting that there is less fresh intake of commercial DDT products and a possible exposure to dicofol in China. CHL and PCB levels were relatively higher in mothers from Japan, whereas beta-HCH and HCB were more common in Chinese women. In Japan. it is suspected that mothers in the urban/coastal area (Sendai) were more continuously exposed to organochlorine pesticides (OCPs) than mothers in the rural/inland area (Takayama). In addition, OCP levels in primiparae were significantly higher than those in multiparae from Japan and Korea. These indicate that both parity and regional factors are major determinants of the levels of OCPs and PCBs in human milk. On the other hand, higher concentrations of PBDEs were observed in mothers′ milk from Korea. The congener was dominated by BDE-47 (43-54%), followed by BDE-153 (23-33%) in all regions except for Beijing where BDE-28 (23%) was relatively abundant. In Japanese breast milk, regional and parity-dependent distributions were not observed for PBDEs. Among PBDE congeners, age-dependency was observed for BDE-153, which was negatively correlated (p<0.05) to the age of mothers in Kyoto (17 participants were housewives), while it increased with age in Sendai (10 participants were clerks). No such correlation was seen for BDE-47. indicating that BDE-47 was ingested and assimilated via different kinetics or routes from BDE-153 in Japan. (C) 2009 Elsevier Ltd. All rights reserved.

语种: 英语
所属项目编号: 1300001 ; 19310042 ; 20404006
项目资助者: Japan Science and Technology Agency ; Scientific Research ; Japan Society for the Promotion of Science
WOS记录号: WOS:000270312600012
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67177
Appears in Collections:北京大学公共卫生学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Daiichi Coll Pharmaceut Sci, Minami Ku, Fukuoka 8158511, Japan
2.Ijinkai Takeda Gen Hosp, Dept Obstet & Gynecol, Kyoto 6011495, Japan
3.Miyagi Univ Educ, Sendai, Miyagi 9800845, Japan
4.Takayama Red Cross Hosp, Dept Neurosurg, Takayama 5068550, Japan
5.Tohoku Kosai Hosp, Dept Obstet & Gynecol, Sendai, Miyagi 9800803, Japan
6.Kyung Hee Univ, Coll Nursing Sci, Seoul 130701, South Korea
7.Hanoi Med Univ, Dept Sci & Technol, Hanoi, Vietnam
8.Kyoto Univ, Grad Sch Med, Dept Hlth & Environm Sci, Kyoto 6068501, Japan
9.Tokushima Bunri Univ, Kagawa Sch Pharmaceut Sci, Kagawa 7692193, Japan
10.Seoul Metropolitan Govt, Res Inst Publ Hlth & Environm, Seoul 137734, South Korea
11.Catholic Univ Pusan, Dept Ind Hlth, Pusan 609757, South Korea
12.Peking Univ, Sch Publ Hlth, Dept Social Med & Hlth Educ, Beijing 100083, Peoples R China

Recommended Citation:
Haraguchi, Koichi,Koizumi, Akio,Inoue, Kayoko,et al. Levels and regional trends of persistent organochlorines and polybrominated diphenyl ethers in Asian breast milk demonstrate POPs signatures unique to individual countries[J]. ENVIRONMENT INTERNATIONAL,2009,35(7):1072-1079.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Haraguchi, Koichi]'s Articles
[Koizumi, Akio]'s Articles
[Inoue, Kayoko]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Haraguchi, Koichi]‘s Articles
[Koizumi, Akio]‘s Articles
[Inoue, Kayoko]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace