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学科主题: 药物依赖
题名:
Tracking the Evolution of HIV/AIDS in China from 1989-2009 to Inform Future Prevention and Control Efforts
作者: Jia, Zhongwei1,2; Wang, Lu2; Chen, Ray Y.3; Li, Dongmin2; Wang, Lan2; Qin, Qianqian2; Ding, Zhengwei2; Ding, Guowei2; Zang, Chunpeng2; Wang, Ning2
刊名: PLOS ONE
发表日期: 2011-10-05
DOI: 10.1371/journal.pone.0025671
卷: 6, 期:10
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Multidisciplinary Sciences
研究领域[WOS]: Science & Technology - Other Topics
关键词[WOS]: ANTIRETROVIRAL THERAPY ; MIGRANT WORKERS ; HIV ; EPIDEMIOLOGY ; SHANGHAI ; PROGRAM
英文摘要:

Background: To determine policy implications, this analysis tracks the evolution of HIV/AIDS infection across China to understand current trends and potential risk factors.

Methods and Principal Findings: A retrospective study with spatial analytical model and multilevel spatial models was conducted among 326,157 HIV/AIDS cases reported from 1989-2009. The results indicate that the distribution of HIV/AIDS was clustered at the county level with different directional distributions across China from 2003 to 2009. Compared to 2003, by 2009 there was a 122% increase in HIV cases among rural residents, 294% increase among urban residents, 211% increase among migrants, and 237% increase among permanent residents. The overall proportion of HIV by different routes of transmission showed dramatic changes with a 504% increase in sexual transmission of HIV, 90% decrease in blood/plasma transmission, and 35% decrease in injecting drug user transmission. Sexual transmission was the major transmission route among women (44%) and the elderly (59% in men, 44% in women) as well as among permanent (36%) and urban residents (33%). Among those < 65 years old, women increased more than men, but among those >= 65 years, men increased more than women. Migrants contributed to the variance of HIV infection between counties but not within counties. The length of highway and urbanization combined with illiteracy were risk factors for HIV/AIDS.

Conclusions/Significance: Rates of HIV/AIDS among permanent urban residents, particularly women and elderly men, have increased significantly in recent years. To prevent HIV from spreading further among the general population, additional attention should be paid to these populations as well as to migrants.

语种: 英语
所属项目编号: 2008ZX100 (01-003) ; 03-008 ; 30973981 ; R24 TW007988 ; KM201010025010
项目资助者: Eleventh Five-year Plan ; National Natural Science Foundation ; U.S. NIH Fogarty ; Beijing Municipal Commission of Education
WOS记录号: WOS:000295966900042
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67191
Appears in Collections:中国药物依赖性研究所_期刊论文

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作者单位: 1.Peking Univ, Natl Inst Drug Dependence, Beijing 100871, Peoples R China
2.China CDC, Natl Ctr AIDS STD Control & Prevent, Beijing, Peoples R China
3.US Embassy, NIAID, US Natl Inst Hlth, Beijing, Peoples R China

Recommended Citation:
Jia, Zhongwei,Wang, Lu,Chen, Ray Y.,et al. Tracking the Evolution of HIV/AIDS in China from 1989-2009 to Inform Future Prevention and Control Efforts[J]. PLOS ONE,2011,6(10).
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