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学科主题: 临床医学
题名:
FTIR spectroscopic explorations of clinical practice of breast cancer
作者: Ling, XF; Xu, Z; Xu, YZ; Li, QB; Zhou, S; Zhang, L; Zhao, HM; Hou, CS; Wang, LX; Hou, KY; Zhou, XS; Wu, JG
关键词: FTIR ; breast cancer ; clinical application exploration
刊名: SPECTROSCOPY AND SPECTRAL ANALYSIS
发表日期: 2005-02-01
卷: 25, 期:2, 页:198-200
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Spectroscopy
研究领域[WOS]: Spectroscopy
关键词[WOS]: TISSUES
英文摘要:

The authors detected ten normal breast tissue samples and eight breast cancer samples by FTIR spectroscopy with an ATR probe. Nineteen variables of thirteen bands in the spectra were compared using standard statistic methods. The results demonstrated that bands of protein, lipid, carbohydrate, and nucleic acid from cancerous samples were significantly different from those from normal ones: (1) The relative intensity of N-H band increased and amide I band shifted to lower wave number significantly; (2)Symmetric and antisyrnmetric vibrations of -CH2 group, C = O vibration, and relative intensity of (-CH2), decreased; (3)The intensity of 1 160 cm(-1) band was much weaker than that of 1 120 cm(-1);(4) The band of P = O or P-O-C shifted toward lower wave number. The authors believe that FTIR spectroscopy has a promising future in breast cancer diagnosis.

语种: 中文
WOS记录号: WOS:000227457500011
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67231
Appears in Collections:北京大学第三临床医学院_普通外科_期刊论文

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作者单位: 1.Peking Univ, Hosp 3, Dept Gen Surg, Beijing 100083, Peoples R China
2.Peking Univ, Coll Chem, Beijing 100871, Peoples R China

Recommended Citation:
Ling, XF,Xu, Z,Xu, YZ,et al. FTIR spectroscopic explorations of clinical practice of breast cancer[J]. SPECTROSCOPY AND SPECTRAL ANALYSIS,2005,25(2):198-200.
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