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学科主题: 药学
题名:
Differentiation of Cuscuta chinensis and Cuscuta australis by HPLC-DAD-MS Analysis and HPLC-UV Quantitation
作者: He, Xianghui; Yang, Wenzhi; Ye, Min; Wang, Qing; Guo, Dean
关键词: Cuscuta chinensis Lam. ; Cuscuta australis R. Br. ; Convolvulaceae ; Chinese herbal medicine ; quality control ; HPLC-DAD-MS
刊名: PLANTA MEDICA
发表日期: 2011-11-01
DOI: 10.1055/s-0030-1271186
卷: 77, 期:17, 页:1950-1957
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]: Plant Sciences ; Pharmacology & Pharmacy
关键词[WOS]: MASS-SPECTROMETRY
英文摘要:

Cuscuta chinensis and Cuscuta australis, the two botanical sources of the Chinese herbal medicine Tu-Si-Zi, were distinguished from each other based on qualitative and quantitative chemical analysis. By HPLC-DAD-MS, a total of 36 compounds were characterized from these two Cuscuta species, including 14 flavonoids, 17 quinic acid derivatives, and 5 lignans. In addition, HPLC-UV was applied to determine seven major compounds (6 flavonoids plus chlorogenic acid) in 27 batches of Tu-Si-Zi. The results revealed that the amounts of the three classes of compounds varied significantly between the species. C. australis contained more flavonoids but less quinic acid derivatives and lignans than C. chinensis. Particularly, the amounts of kaempferol and astragalin in C. australis were remarkably higher than in C. chinensis. This finding could be valuable for the quality control of Tu-Si-Zi.

语种: 英语
所属项目编号: 985-2-119-121
项目资助者: Peking University Health Science Center
WOS记录号: WOS:000298851200015
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67240
Appears in Collections:北京大学药学院_期刊论文

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作者单位: Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

Recommended Citation:
He, Xianghui,Yang, Wenzhi,Ye, Min,et al. Differentiation of Cuscuta chinensis and Cuscuta australis by HPLC-DAD-MS Analysis and HPLC-UV Quantitation[J]. PLANTA MEDICA,2011,77(17):1950-1957.
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