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学科主题临床医学
Protein-templated gold nanoclusters based sensor for off-on detection of ciprofloxacin with a high selectivity
Chen, Zhanguang1; Qian, Sihua1; Chen, Junhui2; Cai, Jie1; Wu, Shuyan1; Cai, Ziping1
关键词Gold nanoclusters Ciprofloxacin Fluorescence Quenching Restoration
刊名TALANTA
2012-05-30
DOI10.1016/j.talanta.2012.03.033
94页:240-245
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Analytical
研究领域[WOS]Chemistry
关键词[WOS]LIGHT-SCATTERING TECHNIQUE ; SILVER NANOCLUSTERS ; LIQUID-CHROMATOGRAPHY ; METAL-IONS ; FLUORESCENCE ; IDENTIFICATION ; WATER
英文摘要

In this contribution, bovine serum albumin stabilized gold nanoclusters as novel fluorescent probes were successfully utilized for the detection of ciprofloxacin for the first time. Our prepared gold nanoclusters exhibited strong emission with peak maximum at 635 nm. Cu2+ was employed to quench the strong fluorescence of the gold nanoclusters, whereas the addition of ciprofloxacin caused the fluorescence intensity restoration of the Cu2+-gold nanoclusters system. The increase in fluorescence intensity of Cu2+-gold nanoclusters system caused by ciprofloxacin allows the sensitive detection of ciprofloxacin in the range of 0.4 ng mL(-1) to 50 ng mL(-1). The detection limit for ciprofloxacin is 0.3 ng mL(-1) at a signal-to-noise ratio of 3. The present sensor for ciprofloxacin detection possesses a low detection limit and wide linear range. In addition, the real samples were analyzed with satisfactory results. (C) 2012 Elsevier B.V. All rights reserved.

语种英语
WOS记录号WOS:000305167300036
项目编号9151022501000019
资助机构Natural Science Foundation of Guangdong Province
引用统计
被引频次:23[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67270
专题北京大学深圳医院
作者单位1.Shantou Univ, Dept Chem, Shantou 515063, Peoples R China
2.Peking Univ, Shenzhen Hosp, Intervent Oncol & Minimally Invas Therapies Dept, Shenzhen 518036, Peoples R China
推荐引用方式
GB/T 7714
Chen, Zhanguang,Qian, Sihua,Chen, Junhui,et al. Protein-templated gold nanoclusters based sensor for off-on detection of ciprofloxacin with a high selectivity[J]. TALANTA,2012,94:240-245.
APA Chen, Zhanguang,Qian, Sihua,Chen, Junhui,Cai, Jie,Wu, Shuyan,&Cai, Ziping.(2012).Protein-templated gold nanoclusters based sensor for off-on detection of ciprofloxacin with a high selectivity.TALANTA,94,240-245.
MLA Chen, Zhanguang,et al."Protein-templated gold nanoclusters based sensor for off-on detection of ciprofloxacin with a high selectivity".TALANTA 94(2012):240-245.
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