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学科主题: 临床医学
题名:
Protein-templated gold nanoclusters based sensor for off-on detection of ciprofloxacin with a high selectivity
作者: Chen, Zhanguang1; Qian, Sihua1; Chen, Junhui2; Cai, Jie1; Wu, Shuyan1; Cai, Ziping1
关键词: Gold nanoclusters ; Ciprofloxacin ; Fluorescence ; Quenching ; Restoration
刊名: TALANTA
发表日期: 2012-05-30
DOI: 10.1016/j.talanta.2012.03.033
卷: 94, 页:240-245
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Analytical
研究领域[WOS]: Chemistry
关键词[WOS]: LIGHT-SCATTERING TECHNIQUE ; SILVER NANOCLUSTERS ; LIQUID-CHROMATOGRAPHY ; METAL-IONS ; FLUORESCENCE ; IDENTIFICATION ; WATER
英文摘要:

In this contribution, bovine serum albumin stabilized gold nanoclusters as novel fluorescent probes were successfully utilized for the detection of ciprofloxacin for the first time. Our prepared gold nanoclusters exhibited strong emission with peak maximum at 635 nm. Cu2+ was employed to quench the strong fluorescence of the gold nanoclusters, whereas the addition of ciprofloxacin caused the fluorescence intensity restoration of the Cu2+-gold nanoclusters system. The increase in fluorescence intensity of Cu2+-gold nanoclusters system caused by ciprofloxacin allows the sensitive detection of ciprofloxacin in the range of 0.4 ng mL(-1) to 50 ng mL(-1). The detection limit for ciprofloxacin is 0.3 ng mL(-1) at a signal-to-noise ratio of 3. The present sensor for ciprofloxacin detection possesses a low detection limit and wide linear range. In addition, the real samples were analyzed with satisfactory results. (C) 2012 Elsevier B.V. All rights reserved.

语种: 英语
所属项目编号: 9151022501000019
项目资助者: Natural Science Foundation of Guangdong Province
WOS记录号: WOS:000305167300036
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67270
Appears in Collections:北京大学深圳医院_期刊论文

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作者单位: 1.Shantou Univ, Dept Chem, Shantou 515063, Peoples R China
2.Peking Univ, Shenzhen Hosp, Intervent Oncol & Minimally Invas Therapies Dept, Shenzhen 518036, Peoples R China

Recommended Citation:
Chen, Zhanguang,Qian, Sihua,Chen, Junhui,et al. Protein-templated gold nanoclusters based sensor for off-on detection of ciprofloxacin with a high selectivity[J]. TALANTA,2012,94:240-245.
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