IR@PKUHSC  > 北京大学第三临床医学院  > 麻醉科
学科主题临床医学
Effective background infusion rate of ropivacaine 0.2% for patient-controlled interscalene brachial plexus analgesia after rotator cuff repair surgery
Wei Yue; Li Min; Rong Yulan; Guo Xiangyang
关键词ropivacaine brachial plexus nerve block dose-response relationship drug
刊名CHINESE MEDICAL JOURNAL
2014-12-05
DOI10.3760/cma.j.issn.0366-6999.20141745
127期:23页:4119-4123
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal
资助者Chinese Society of Anesthesiology Li Bang Foundation ; Chinese Society of Anesthesiology Li Bang Foundation
研究领域[WOS]General & Internal Medicine
关键词[WOS]OPEN SHOULDER SURGERY ; MINIMUM EFFECTIVE VOLUME ; POSTOPERATIVE ANALGESIA ; NERVE BLOCKS ; PERINEURAL INFUSION ; RANDOMIZED-TRIAL ; MOTOR FUNCTION ; DOUBLE-BLIND ; DOWN DESIGN ; ULTRASOUND
英文摘要

Background Continuous interscalene nerve block (CISB) is considered to be the most effective method for postoperative analgesia after shoulder surgery with prolonged severe pain. This study was performed to evaluate the minimum effective background infusion rate and the effective background infusion rate of ropivacaine 0.2% for CISB after arthroscopic rotator cuff repair surgery in 95% of patients.

Methods Patients scheduled for arthroscopic rotator cuff repair surgery under general anesthesia at Peking University Third Hospital were prospectively enrolled from December 2011 to May 2012. Preoperatively, an interscalene catheter (ISC) was placed under the guidance of ultrasound and nerve stimulation in each patient. Consecutively, 30 patients with successful nerve block were included. A continuous infusion of ropivacaine 0.2% with a 5 ml patient-controlled bolus available hourly was started at postoperative anesthesia care unit (PACU) after completion of surgery. The initial background infusion rate was 6 ml/h, which was subsequently varied for each consecutive patient according to the analgesic effects of the previous one. The minimum effective background rate was determined using the Dixon and Massey up-and-down method. The effective background rate in 95% of patients was calculated using isotonic analysis.

Results The minimum effective background rate based on the Dixon and Massey up-and-down method was 2.8 ml/h (95% Cl, 2.3-3.3 ml/h). The effective background rate in 95% of patients calculated with the isotonic regression analysis was 4.4 ml/h (95% Cl, 3.8-6.5 ml/h).

Conclusion The effective background rate for patient-controlled interscalene brachial plexus analgesia after shoulder surgery in 50% and 95% of the patients was 2.8 and 4.4 ml/h, respectively.

语种英语
所属项目编号CSA2010LB010
资助者Chinese Society of Anesthesiology Li Bang Foundation ; Chinese Society of Anesthesiology Li Bang Foundation
WOS记录号WOS:000347276500022
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67272
Collection北京大学第三临床医学院_麻醉科
作者单位Peking Univ, Hosp 3, Dept Anesthesiol, Beijing 100191, Peoples R China
Recommended Citation
GB/T 7714
Wei Yue,Li Min,Rong Yulan,et al. Effective background infusion rate of ropivacaine 0.2% for patient-controlled interscalene brachial plexus analgesia after rotator cuff repair surgery[J]. CHINESE MEDICAL JOURNAL,2014,127(23):4119-4123.
APA Wei Yue,Li Min,Rong Yulan,&Guo Xiangyang.(2014).Effective background infusion rate of ropivacaine 0.2% for patient-controlled interscalene brachial plexus analgesia after rotator cuff repair surgery.CHINESE MEDICAL JOURNAL,127(23),4119-4123.
MLA Wei Yue,et al."Effective background infusion rate of ropivacaine 0.2% for patient-controlled interscalene brachial plexus analgesia after rotator cuff repair surgery".CHINESE MEDICAL JOURNAL 127.23(2014):4119-4123.
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