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学科主题: 临床医学
题名:
Determination of fluid status in haemodialysis patients with whole body and calf bioimpedance techniques
作者: Liu, Li1,2,3; Zhu, Fansan1,2; Raimann, Jochen G.1,2; Thijssen, Stephan1,2; Sipahioglu, Murat H.1,2; Wystrychowski, Gregory1,2; Kitzler, Thomas1,2; Tetta, Ciro4; Wabel, Peter4; Kotanko, Peter1,2; Levin, Nathan W.1,2
关键词: calf bioimpedance spectroscopy ; dry weight ; excess fluid volume ; haemodialysis ; whole body bioimpedance spectroscopy
刊名: NEPHROLOGY
发表日期: 2012-02-01
DOI: 10.1111/j.1440-1797.2011.01526.x
卷: 17, 期:2, 页:131-140
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Urology & Nephrology
研究领域[WOS]: Urology & Nephrology
关键词[WOS]: BIOELECTRICAL-IMPEDANCE ANALYSIS ; PERITONEAL-DIALYSIS PATIENTS ; POSTDIALYSIS DRY-WEIGHT ; BLOOD-PRESSURE CONTROL ; EXTRACELLULAR VOLUME ; WATER COMPARTMENTS ; CELL MASS ; SPECTROSCOPY ; HYDRATION ; POPULATION
英文摘要:

Aim: The aim of this study was to demonstrate the ability of widely used bioimpedance techniques to assess dry weight (DW) and to predict a state of normal hydration in haemodialysis patients whose post-dialysis weight had been gradually reduced from baseline in successive treatments over time. Methods: Calf bioimpedance spectroscopy (cBIS) was employed to determine DW (DWcBIS) as defined by flattening of an intradialytic continuously measured resistance curve and by normalized resistivity (nRho) being in the gender-specific normal range. The wECV/ TBW ratio was determined by ` classical′ wrist-to-ankle whole body bioimpedance spectroscopy (wBIS); in addition, a novel whole body model (WBM) based on wBIS was used to predict normal hydration weight (NHWWBM). Results: Twenty-one haemodialysis patients were studied; 11 1 6 measurements were performed per patient. Nine patients reached DWcBIS (DWcBIS group), while 12 patients remained fluid-overloaded (non-DWcBIS group). Change in wECV as measured by wBIS accounted for 46 1 23% in DWcBIS group, which was higher than in non-DWcBIS group (33 1 48%, P < 0.05) of actual weight loss at the end of study. In both groups the wECV/ TBW ratio did not change significantly between baseline and study end. Mean predicted NHWWBM at baseline was 3.55 1 1.6 kg higher than DWcBIS. The difference in DWcBIS and NHWWBM was 1.97 1 1.0 kg at study end. Conclusion: WBM could be useful to predict a target range of normal hydration weight particularly for patients with substantial fluid overload. The cBIS provides an accurate reference for the estimation of DW so that combined use of cBIS and WBM is promising and warrants further studies.

语种: 英语
项目资助者: Renal Research Institute
WOS记录号: WOS:000299252400005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67320
Appears in Collections:北京大学第一临床医学院_肾脏内科_期刊论文

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作者单位: 1.Beth Israel Deaconess Med Ctr, Renal Res Inst, New York, NY 10003 USA
2.Beth Israel Deaconess Med Ctr, Div Nephrol & Hypertens, New York, NY 10003 USA
3.Peking Univ, Renal Div, Hosp 1, Beijing 100871, Peoples R China
4.Fresenius Med Care, Bad Homburg, Germany

Recommended Citation:
Liu, Li,Zhu, Fansan,Raimann, Jochen G.,et al. Determination of fluid status in haemodialysis patients with whole body and calf bioimpedance techniques[J]. NEPHROLOGY,2012,17(2):131-140.
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