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学科主题: 临床医学
题名:
Inadequate glycaemic control and antidiabetic therapy among inpatients with type 2 diabetes in Guangdong Province of China
作者: Bi Yan2,3,4; Yan Jin-hua2; Liao Zhi-hong2; Li Yan-Bing2; Zeng Long-yi3,4; Tang Kuan-xiao2; Xue Yao-ming5; Yang Hua-Zhang6; Li Lu7; Cai De-hong8; Wu Ge; Zhang Fan9; Lin Shao-da10; Xiao Zheng-hua11; Zhu Da-long1; Weng Jian-ping4
关键词: type 2 diabetes ; inpatient ; glycaemic control ; antidiabetic therapy
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2008-04-20
卷: 121, 期:8, 页:677-681
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: ACUTE MYOCARDIAL-INFARCTION ; BLOOD-GLUCOSE CONTROL ; NO PREVIOUS DIAGNOSIS ; CONSENSUS STATEMENT ; MELLITUS ; COMPLICATIONS ; HYPERGLYCEMIA ; ASSOCIATION ; PREVALENCE ; MANAGEMENT
英文摘要:

Background Diabetes mellitus has become epidemic in recent years in China. We investigated the prevalence of hyperglycaemia and inadequate glycaemic control among type 2 diabetic inpatients from ten university teaching hospitals in Guangdong Province, China.

Methods Inadequate glycaemic control in diabetic patients was defined as HbA1c >= 6.5%. Therapeutic regimens included no-intervention, lifestyle only, oral antiglycemic agents (OA), insulin plus OA (insulin+OA), or insulin only. Antidiabetic managements included monotherapy, double therapy, triple or quadruple therapy.

Results Among 493 diabetic inpatients with known history, 75% had HbA1c >= 6.5%. Inadequate glucose control rates were more frequently seen in patients on insulin+OA regimen (97%),than on OA regimen (71%) (P < 0.001), and more frequent in patients on combination therapy (81%-96%) than monotherapy (75%) (P < 0.05). Patients on insulin differed significantly from patients on OA by mean HbA1c, glycemic control rate, diabetes duration, microvascular complications, and BMI (P < 0.01).

Conclusions This study showed that glycaemic control of type 2 diabetic patients deteriorated for patients who received insulin and initiation time of insulin was usually delayed. It is up to clinicians to move from the traditional stepwise therapy to a more active and early combination antidiabetic therapy to provide better glucose control.

语种: 英语
WOS记录号: WOS:000255497400002
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67344
Appears in Collections:北京大学深圳医院_内分泌科_期刊论文

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作者单位: 1.Nanjing Univ, Drum Tower Hosp Affiliated Med Coll, Dept Endocrinol, Nanjing 210008, Peoples R China
2.Sun Yat Sen Univ, Affiliated Hosp 1, Dept Endocrinol, Guangzhou 510080, Guangdong, Peoples R China
3.Sun Yat Sen Univ, Affiliated Hosp 3, Dept Endocrinol, Guangzhou 510630, Guangdong, Peoples R China
4.So Med Univ, Nanfang Hosp, Dept Endocrinol, Guangzhou 510515, Guangdong, Peoples R China
5.Guangdong Prov Peoples Hosp, Dept Endocrinol, Guangzhou 510080, Guangdong, Peoples R China
6.Jinan Univ, Coll Med, Shenzhen Peoples Hosp, Dept Endocrinol, Shenzhen 518020, Peoples R China
7.So Med Univ, Zhujiang Hosp, Dept Endocrinol, Guangzhou 510282, Guangdong, Peoples R China
8.Affiliated Hosp, Guangdong Med Coll, Dept Endocrinol, Guangzhou 524001, Guangdong, Peoples R China
9.Peking Univ, Shenzhen Hosp, Dept Endocrinol, Shenzhen 518036, Guangdong, Peoples R China
10.Shantou Univ, Coll Med, Affiliated Hosp, Dept Endocrinol, Shantou 515041, Guangdong, Peoples R China
11.Guangzhou First Municipal Peoples Hosp, Dept Endocrinol, Guangzhou 510180, Guangdong, Peoples R China

Recommended Citation:
Bi Yan,Yan Jin-hua,Liao Zhi-hong,et al. Inadequate glycaemic control and antidiabetic therapy among inpatients with type 2 diabetes in Guangdong Province of China[J]. CHINESE MEDICAL JOURNAL,2008,121(8):677-681.
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