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学科主题: 基础医学
题名:
Rheology characteristics of erythrocytes under the influence of calcium ions and ionophore A23187
作者: Wang, CY; Zeng, YJ; Wen, ZY; Ka, WB; Yao, WJ; Liao, DH
关键词: new ektacytometry ; calcium ions ; ionophore A23187 ; erythrocyte deformation
刊名: PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
发表日期: 2001-12-01
卷: 28, 期:6, 页:870-873
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biochemistry & Molecular Biology ; Biophysics
研究领域[WOS]: Biochemistry & Molecular Biology ; Biophysics
关键词[WOS]: SHEAR-FLOW ; MEMBRANE ; DEFORMABILITY ; PERMEABILIZATION
英文摘要:

In order to study effect of extracellular Ca2+ and ionophore A23187 on erythrocyte deformation, the new ektacytometry is used. After erythrocytes were treated with different concentrations of intercellular Ca2+ and ionophore A23187 respectively, the orientation index ( DI)(or) and small deformation index ( DI)(d) of the erythrocytes were measured. It is suggested that the effect of ionophore A23187 on the rheology of erythrocytes is more notable than that of intercellular Ca2+. Furthermore, the ( DI)(or,max) and ( DI)(d,max) decrease as the concentration of intercellular Ca2+ or ionophore A23187 is increased. The deformability of erythrocytes was obviously reduced after treated with ionophore A23187.

语种: 中文
WOS记录号: WOS:000172947500024
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67358
Appears in Collections:基础医学院_生物物理学系_期刊论文

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作者单位: 1.Beijing Polytech Univ, Ctr Biomed, Beijing 100022, Peoples R China
2.Peking Univ, Sch Med, Dept Biophys, Beijing 100083, Peoples R China

Recommended Citation:
Wang, CY,Zeng, YJ,Wen, ZY,et al. Rheology characteristics of erythrocytes under the influence of calcium ions and ionophore A23187[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2001,28(6):870-873.
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