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学科主题: 临床医学
题名:
Prognosis of unclassified eczema - A follow-up study
作者: Li, Lin-feng; Liu, Guangren; Wang, Jing
刊名: ARCHIVES OF DERMATOLOGY
发表日期: 2008-02-01
卷: 144, 期:2, 页:160-164
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Dermatology
研究领域[WOS]: Dermatology
关键词[WOS]: ENDOGENOUS ECZEMA ; DERMATITIS
英文摘要:

Objective: To investigate the outcome of unclassified eczema (UE). Eczema refers to a set of highly heterogeneous clinical conditions including contact dermatitis (CD) and several types of endogenous eczema. In clinics, however, the eczema of a large proportion of patients does not fit any known patterns and has been diagnosed as unclassified eczema. The prognosis of UE is largely unknown.

Design: Cohort study with I-year follow-up.

Setting: Dermatology clinic in Peking University Third Hospital, Beijing, China.

Patients: All cases of UE in 655 consecutive patients with eczema patch tested with the European Standard series occurring during a 2-year period. Interventions: At I year after patch testing, all patients were asked to revisit the clinic, and 599 patients returned (91.5%); of these, 192 had UE (32.1%).

Main Outcome Measures: The rate of symptom-free skin for at least 3 months without relapse before evaluation.

Results: During the follow-up period, only 15.1% of patients, with UE had their lesions cleared, which was a much lower rate than for those with CD (50.4%) (P <.00 1; chi(2) test) but close to the rate of those with atopic dermatitis (7.1%). A to tal of 11.0% of patients with UE had atopic diathesis, and 72.4% of those with UE had a positive reaction to at least 1 contact allergen, which was a lower rate than that of patients with allergic CD (88.6%) but higher than that for patients with irritant CD (53.8%) (P <.001 and P=.004, respectively; chi(2) test); however, none of these results were relevant to eczema.

Conclusions: Unclassified eczema is a common type of eczema with a very poor prognosis. This important category of eczema should be recognized and studied further.

语种: 英语
WOS记录号: WOS:000253164900003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67432
Appears in Collections:北京大学第三临床医学院_皮肤科_期刊论文

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作者单位: Peking Univ Third Hosp, Dept Dermatol, Beijing 100083, Peoples R China

Recommended Citation:
Li, Lin-feng,Liu, Guangren,Wang, Jing. Prognosis of unclassified eczema - A follow-up study[J]. ARCHIVES OF DERMATOLOGY,2008,144(2):160-164.
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