IR@PKUHSC  > 北京大学第一临床医学院  > 临床药理研究所
学科主题临床医学
Molecular characterization of vancomycin-resistant Enterococcus faecium isolates from mainland China
Zheng, Bo; Tomita, Haruyoshi; Xiao, Yong Hong; Wang, Shan; Li, Yun; Ike, Yasuyoshi
刊名JOURNAL OF CLINICAL MICROBIOLOGY
2007-09-01
DOI10.1128/JCM.00457-07
45期:9页:2813-2818
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Microbiology
研究领域[WOS]Microbiology
关键词[WOS]VANA GLYCOPEPTIDE RESISTANCE ; TN1546-LIKE ELEMENTS ; STREPTOCOCCUS-FAECALIS ; SEX-PHEROMONES ; PLASMID ; HUMANS ; IDENTIFICATION ; DIVERSITY ; JAPAN ; GENE
英文摘要

Little is known about vancomycin-resistant enterococei in China. Thirteen pulsed-field gel electrophoresis-confirmed heterogeneous VanA-type vancomycin-resistant Enterococcus faecium (VRF) isolates were obtained from five Chinese hospitals from 2.001 to 2005. The isolates were typed by multilocus sequence typing into nine different sequence types (STs), including five new STs (ST18, ST25, ST78, ST203, ST320, ST321, ST322, ST323, and ST335). Vancomycin resistance in each isolate was encoded on conjugative plasmids; two of the plasmids, pZB18 (67 kbp) and pZB22 (200.kbp), were highly conjugative and were able to transfer at high frequencies of around 10(-4) and 10(-7) per donor cell in broth mating, respectively. None of the plasmids identified in these isolates carried traA, which is usually conserved in the pMG1-like highly conjugative plasmid for E. faecium, implying that pZB18 and pZB22 were novel types of a highly conjugative plasmid in enterococci. Thirteen Tn1546-like elements encoding VanA-type VRE on the conjugative plasmids were classified into six types (types I to VI), and most of them contained both IS1216V and IS1542 insertions. The isolates carrying the type 11 element were predominant. The six type elements were different from that of a VanA-type Enterococcus faecalis strain isolated from Chinese chicken meat. The results suggested that the disseminations of VRE in these areas were by Tn1546-like elements being acquired by the conjugative plasmids and transferred among E. faecium strains.

语种英语
WOS记录号WOS:000249506900010
引用统计
被引频次:36[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67463
专题北京大学第一临床医学院_临床药理研究所
作者单位1.Gunma Univ, Grad Sch Med, Dept Bacteriol & Bacterial Infect Control, Gunma 3718511, Japan
2.Peking Univ First Hosp, Inst Clin Pharmacol, Beijing 100034, Peoples R China
3.Gunma Univ, Grad Sch Med, Lab Bacterial Drug Resistance, Gunma 3718511, Japan
推荐引用方式
GB/T 7714
Zheng, Bo,Tomita, Haruyoshi,Xiao, Yong Hong,et al. Molecular characterization of vancomycin-resistant Enterococcus faecium isolates from mainland China[J]. JOURNAL OF CLINICAL MICROBIOLOGY,2007,45(9):2813-2818.
APA Zheng, Bo,Tomita, Haruyoshi,Xiao, Yong Hong,Wang, Shan,Li, Yun,&Ike, Yasuyoshi.(2007).Molecular characterization of vancomycin-resistant Enterococcus faecium isolates from mainland China.JOURNAL OF CLINICAL MICROBIOLOGY,45(9),2813-2818.
MLA Zheng, Bo,et al."Molecular characterization of vancomycin-resistant Enterococcus faecium isolates from mainland China".JOURNAL OF CLINICAL MICROBIOLOGY 45.9(2007):2813-2818.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Zheng, Bo]的文章
[Tomita, Haruyoshi]的文章
[Xiao, Yong Hong]的文章
百度学术
百度学术中相似的文章
[Zheng, Bo]的文章
[Tomita, Haruyoshi]的文章
[Xiao, Yong Hong]的文章
必应学术
必应学术中相似的文章
[Zheng, Bo]的文章
[Tomita, Haruyoshi]的文章
[Xiao, Yong Hong]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。