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Photoresponsive Cross-linked Polymeric Particles for Phototriggered Burst Release
Wang, Zhen1; Yu, Lili2; Lv, Cong1; Wang, Peng1; Chen, Yedong1; Tang, Xinjing1
刊名PHOTOCHEMISTRY AND PHOTOBIOLOGY
2013-05-01
DOI10.1111/php.12038
89期:3页:552-559
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Biophysics
研究领域[WOS]Biochemistry & Molecular Biology ; Biophysics
关键词[WOS]BLOCK-COPOLYMER MICELLES ; DRUG-DELIVERY SYSTEMS ; TRIGGERED RELEASE ; DIBLOCK COPOLYMER ; LIGHT ; NANOPARTICLES ; DEGRADATION ; MECHANISMS ; HYDROGELS ; PHOTO
英文摘要

We synthesized a series of cross-linked photoresponsive polymeric particles with photolabile monomers and cross-linkers through miniemulsion polymerization. These particles are quite stable in dark, while light irradiation caused the breakage of particles and the efficient release of encapsulated contents up to 95% based on Nile red fluorescence. Photoswitches of particle systems were confirmed by fluorescence spectroscopy, SEM and colorimetry. Particle uptake and triggered release in RAW264.7 cells were confirmed by fluorescein diacetate loaded particles.

语种英语
WOS记录号WOS:000318232800005
项目编号BMU20110263 ; 20100001120051 ; 21072015 ; NCET-100203
资助机构Innovation Team of Ministry of Education ; Higher Education Doctoral Fund of Ministry of Education of China ; National Natural Science Foundation of China ; Program for New Century Excellent Talents in University
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67503
专题北京大学药学院
北京大学医学部管理机构_医学部
作者单位1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
2.Xian Med Univ, Sch Pharmaceut Sci, Xian 710021, Shanxi, Peoples R China
推荐引用方式
GB/T 7714
Wang, Zhen,Yu, Lili,Lv, Cong,et al. Photoresponsive Cross-linked Polymeric Particles for Phototriggered Burst Release[J]. PHOTOCHEMISTRY AND PHOTOBIOLOGY,2013,89(3):552-559.
APA Wang, Zhen,Yu, Lili,Lv, Cong,Wang, Peng,Chen, Yedong,&Tang, Xinjing.(2013).Photoresponsive Cross-linked Polymeric Particles for Phototriggered Burst Release.PHOTOCHEMISTRY AND PHOTOBIOLOGY,89(3),552-559.
MLA Wang, Zhen,et al."Photoresponsive Cross-linked Polymeric Particles for Phototriggered Burst Release".PHOTOCHEMISTRY AND PHOTOBIOLOGY 89.3(2013):552-559.
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