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学科主题: 药学
题名:
Photoresponsive Cross-linked Polymeric Particles for Phototriggered Burst Release
作者: Wang, Zhen1; Yu, Lili2; Lv, Cong1; Wang, Peng1; Chen, Yedong1; Tang, Xinjing1
刊名: PHOTOCHEMISTRY AND PHOTOBIOLOGY
发表日期: 2013-05-01
DOI: 10.1111/php.12038
卷: 89, 期:3, 页:552-559
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Biochemistry & Molecular Biology ; Biophysics
研究领域[WOS]: Biochemistry & Molecular Biology ; Biophysics
关键词[WOS]: BLOCK-COPOLYMER MICELLES ; DRUG-DELIVERY SYSTEMS ; TRIGGERED RELEASE ; DIBLOCK COPOLYMER ; LIGHT ; NANOPARTICLES ; DEGRADATION ; MECHANISMS ; HYDROGELS ; PHOTO
英文摘要:

We synthesized a series of cross-linked photoresponsive polymeric particles with photolabile monomers and cross-linkers through miniemulsion polymerization. These particles are quite stable in dark, while light irradiation caused the breakage of particles and the efficient release of encapsulated contents up to 95% based on Nile red fluorescence. Photoswitches of particle systems were confirmed by fluorescence spectroscopy, SEM and colorimetry. Particle uptake and triggered release in RAW264.7 cells were confirmed by fluorescein diacetate loaded particles.

语种: 英语
所属项目编号: BMU20110263 ; 20100001120051 ; 21072015 ; NCET-100203
项目资助者: Innovation Team of Ministry of Education ; Higher Education Doctoral Fund of Ministry of Education of China ; National Natural Science Foundation of China ; Program for New Century Excellent Talents in University
WOS记录号: WOS:000318232800005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67503
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
2.Xian Med Univ, Sch Pharmaceut Sci, Xian 710021, Shanxi, Peoples R China

Recommended Citation:
Wang, Zhen,Yu, Lili,Lv, Cong,et al. Photoresponsive Cross-linked Polymeric Particles for Phototriggered Burst Release[J]. PHOTOCHEMISTRY AND PHOTOBIOLOGY,2013,89(3):552-559.
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