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Tardive dyskinesia in the treatment of schizophrenia: the findings of the Research on Asian Psychotropic Prescription Pattern (REAP) survey (2001-2009)
Xiang, Y. -T.1,2; Wang, C. -Y.2; Si, T. -M.3; Lee, E. H. M.1; He, Y. -L.4; Ungvari, G. S.5; Chiu, H. F. K.1; Yang, S. -Y.6; Chong, M. -Y.7,8; Tan, C. -H.9; Kua, E. -H.9; Fujii, S.10; Sim, K.11; Yong, K. H.11; Trivedi, J. K.12; Chung, E. -K.13; Udomratn, P.14; Chee, K. -Y.15; Sartorius, N.16; Shinfuku, N.17
关键词schizophrenia tardive dyskinesia ethnicity
刊名INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
2011-06-01
DOI10.5414/CP201505
49期:6页:382-387
收录类别SCI ; SSCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Pharmacology & Pharmacy
资助者National Science Foundation ; Beijing Municipal Science and Technology Commission in China ; Chinese University of Hong Kong in Hong Kong ; Institute of Mental Health Research Grant in Singapore ; Taiwan Bureau of National Health Insurance ; Chang Gung Memorial Hospital ; Taipei City Government in Taiwan ; National Science Foundation ; Beijing Municipal Science and Technology Commission in China ; Chinese University of Hong Kong in Hong Kong ; Institute of Mental Health Research Grant in Singapore ; Taiwan Bureau of National Health Insurance ; Chang Gung Memorial Hospital ; Taipei City Government in Taiwan
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]HEALTH OUTCOMES SOHO ; RISK-FACTORS ; EAST-ASIA ; ANTIPSYCHOTIC TREATMENT ; PSYCHIATRIC-PATIENTS ; GENDER-DIFFERENCES ; NEGATIVE SYMPTOMS ; PREVALENCE ; CHINESE ; NEUROLEPTICS
英文摘要

Objective: The aim of the study was to survey the frequency of tardive dyskinesia (TD) in patients with schizophrenia and its demographic and clinical correlates in selected Asian countries. Method: A total of 6,761 hospitalized schizophrenia patients in nine Asian countries and territories were examined from 2001 to 2009. TD was evaluated as "present" or "absent" according to the clinical judgment of experienced psychiatrists. The patients′ socio-demographic and clinical characteristics and the prescriptions of psychotropic drugs were recorded using a standardized protocol and data collection procedure. Results: The frequency of TD in the whole sample was 5.0% with wide variations between countries (0 - 14.9%). Multiple logistic regression analysis showed that the following variables were independently associated with TD: study time, study site, older age, male gender, more severe negative and extrapyramidal symptoms and less anticholinergic drugs. Conclusions: A generally low frequency of TD in Asian schizophrenia patients with inter-ethnic variations was recorded. It is unclear whether the low prevalence of TD compared with Western data is real or the result of it being insufficiently recognized.

语种英语
所属项目编号30800367 ; 30770776 ; 2008B59 ; 2041454 ; CRC 249/2008 ; DOH92-NH-1025 ; CMRPG83043 ; 97001-62-010
资助者National Science Foundation ; Beijing Municipal Science and Technology Commission in China ; Chinese University of Hong Kong in Hong Kong ; Institute of Mental Health Research Grant in Singapore ; Taiwan Bureau of National Health Insurance ; Chang Gung Memorial Hospital ; Taipei City Government in Taiwan ; National Science Foundation ; Beijing Municipal Science and Technology Commission in China ; Chinese University of Hong Kong in Hong Kong ; Institute of Mental Health Research Grant in Singapore ; Taiwan Bureau of National Health Insurance ; Chang Gung Memorial Hospital ; Taipei City Government in Taiwan
WOS记录号WOS:000292222700005
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67527
专题北京大学精神卫生研究所
作者单位1.CSM Med Univ UP, Dept Psychiat, Lucknow, Uttar Pradesh, India
2.Natl Seoul Hosp, Seoul, South Korea
3.Prince Songkla Univ, Hat Yai, Thailand
4.Univ Geneva, Geneva, Switzerland
5.Seinan Gakuin Univ Fukuoka, Sch Human Sci, Fukuoka, Japan
6.Chinese Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China
7.Capital Med Univ, Beijing Anding Hosp, Beijing, Peoples R China
8.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
9.Shanghai Mental Hlth Ctr, Shanghai, Peoples R China
10.Univ Notre Dame Australia Marian Ctr, Perth, WA, Australia
11.Taipei City Hosp, Taipei, Taiwan
12.Chang Gung Univ, Kaohsiung Chang Gung Mem Hosp, Guishan, Taiwan
13.Chang Gung Univ, Sch Med, Guishan, Taiwan
14.Natl Univ Singapore, Singapore 117548, Singapore
15.HITS, Kobe, Hyogo, Japan
16.Inst Mental Hlth, Bangkok View, Singapore
17.Kuala Lumpur Hosp, Tunku Abdul Rahman Inst Neurosci, Dept Psychiat & Mental Hlth, Kuala Lumpur, Malaysia
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GB/T 7714
Xiang, Y. -T.,Wang, C. -Y.,Si, T. -M.,et al. Tardive dyskinesia in the treatment of schizophrenia: the findings of the Research on Asian Psychotropic Prescription Pattern (REAP) survey (2001-2009)[J]. INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS,2011,49(6):382-387.
APA Xiang, Y. -T..,Wang, C. -Y..,Si, T. -M..,Lee, E. H. M..,He, Y. -L..,...&Shinfuku, N..(2011).Tardive dyskinesia in the treatment of schizophrenia: the findings of the Research on Asian Psychotropic Prescription Pattern (REAP) survey (2001-2009).INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS,49(6),382-387.
MLA Xiang, Y. -T.,et al."Tardive dyskinesia in the treatment of schizophrenia: the findings of the Research on Asian Psychotropic Prescription Pattern (REAP) survey (2001-2009)".INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS 49.6(2011):382-387.
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