IR@PKUHSC  > 北京大学药学院
学科主题药学
Constituents of Vigna angularis and their in vitro anti-inflammatory activity
Jiang, Yong1,2; Zeng, Ke-Wu1; David, Bruno2; Massiot, Georges3
关键词Vigna angularis Leguminosae Furanylmethyl glycosides ent-Kaurane diterpene glycosides Triterpene saponins Anti-inflammatory activity
刊名PHYTOCHEMISTRY
2014-11-01
DOI10.1016/j.phytochem.2014.08.011
107页:111-118
收录类别SCI ; IC
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Plant Sciences
研究领域[WOS]Biochemistry & Molecular Biology ; Plant Sciences
关键词[WOS]BLOOD-PRESSURE ELEVATION ; HOT-WATER EXTRACT ; CHEMICAL-CONSTITUENTS ; WILLD OHWI ; RHEUMATOID-ARTHRITIS ; SEEDS ; GLYCOSIDES ; SAPOGENOL ; SAPONIN ; OHASHI
英文摘要

Nine non-phenolic compounds, including four furanylmethyl glycosides, angularides A-D, one ent-kaurane diterpene glycoside, angularin A, and four triterpenoid saponins, angulasaponins A-D, were isolated from seeds of Vigna angularis, together with eight known compounds. Their structures were elucidated on the basis of extensive 1D and 2D NMR spectroscopic analysis as well as chemical methods. Angularin A, angulasaponins A-C, and azukisaponins III and VI showed inhibition of nitric oxide production in LPS-activated RAW264.7 macrophages, with IC50 values ranging from 13 mu M to 24 mu M. (C) 2014 Elsevier Ltd. All rights reserved.

语种英语
WOS记录号WOS:000343840500013
项目编号81222051 ; 2012ZX09301002-002-002 ; 2012ZX 09304-005
资助机构Fondation Franco-Chinoise pour la Science et ses Applications (FFCSA) ; China Scholarship Council (CSC) ; National Science Fund for Excellent Young Scholars of China ; National Key Technology R&amp ; D Program "New Drug Innovation" of China
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67575
专题北京大学药学院
作者单位1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
2.Inst Rech Pierre Fabre, Pole Actifs Vegetaux, F-31035 Toulouse 1, France
3.USR CNRS, Pierre Fabre ETaC 3388, Ctr Rech & Dev Pierre Fabre, F-31035 Toulouse 01, France
推荐引用方式
GB/T 7714
Jiang, Yong,Zeng, Ke-Wu,David, Bruno,et al. Constituents of Vigna angularis and their in vitro anti-inflammatory activity[J]. PHYTOCHEMISTRY,2014,107:111-118.
APA Jiang, Yong,Zeng, Ke-Wu,David, Bruno,&Massiot, Georges.(2014).Constituents of Vigna angularis and their in vitro anti-inflammatory activity.PHYTOCHEMISTRY,107,111-118.
MLA Jiang, Yong,et al."Constituents of Vigna angularis and their in vitro anti-inflammatory activity".PHYTOCHEMISTRY 107(2014):111-118.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Jiang, Yong]的文章
[Zeng, Ke-Wu]的文章
[David, Bruno]的文章
百度学术
百度学术中相似的文章
[Jiang, Yong]的文章
[Zeng, Ke-Wu]的文章
[David, Bruno]的文章
必应学术
必应学术中相似的文章
[Jiang, Yong]的文章
[Zeng, Ke-Wu]的文章
[David, Bruno]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。