IR@PKUHSC  > 北京大学第三临床医学院  > 消化科
学科主题临床医学
Peptic ulcer bleeding in China: A multicenter endoscopic survey of 1006 patients
Bai, Yu1; Du, Yi Qi1; Wang, Dong1; Zou, Duo Wu1; Jin, Zhen Dong1; Zhan, Xian Bao1; Zhao, Xiao Yan5; Sha, Wei Hong8; Wang, Jiang Bin11; Yu, Weng Fei12; Jiang, Yi13; Ye, Li Ping14; Zhang, Shu Tian16; Zhou, Li Ya17; Chen, Min Hu9; Yu, Xiao Feng2; Zheng, Jian Wei19; Wang, Rong Quan6; Huang, Xiao Jun20; Chen, Dong Feng7; Wang, Hua Hong18; Tian, De An21; Lu, Nong Hua23; Hou, Xiao Hua22; Ji, Feng15; Wang, Ji Yao3; Yuan, Yao Zong4; Fan, Dai Ming24; Wu, Kai Chun24; Jiang, Bo10; Li, Zhao Shen1; Chinese Peptic Ulcer
关键词bleeding endoscopy peptic ulcer
刊名JOURNAL OF DIGESTIVE DISEASES
2014
DOI10.1111/1751-2980.12104
15期:1页:5-11
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Gastroenterology & Hepatology
研究领域[WOS]Gastroenterology & Hepatology
关键词[WOS]EPIDEMIOLOGY ; OUTCOMES
英文摘要

ObjectiveWe aimed to describe the clinical picture, management and outcomes of Chinese patients with peptic ulcer bleeding (PUB), especially in those with high risks.

MethodsA multicenter endoscopic survey was conducted. All consecutive patients with endoscopy confirmed PUB from October 2010 to June 2011 were enrolled. Data including patients′ gender, age, symptoms and endoscopic findings, Forrest classification, and endoscopic and medical treatment were documented. High-risk ulcer was defined as Forrest grades Ia to IIb upon endoscopy. Rates of rebleeding, surgery and mortality were recorded.

ResultsIn all, 1006 patients were included. Of these 437 (43.4%) were categorized with high-risk PUB, among whom 110 (25.2%) received endoscopic treatment, and the success rate was 99.1%. Rebleeding rates 1-3 days, 4-5 days and 6-30 days after treatment in high-risk patients who did and did not receive endoscopic treatment were 10.9% versus 10.4%, 3.6% versus 3.7% and 0.9% versus 1.5%, respectively. The surgery rates of high-risk patients with or without endoscopic treatment were 1.8% (2/110) versus 1.8% (6/327). During the 9-month study period, two patients with high-risk PUB died, therefore, the overall mortality rate of high-risk PUB was 0.5% (2/437).

ConclusionThe study suggests that the proportions of high-risk PUB in China is 43.4%, while rebleeding and surgery rate after endoscopic treatment as well as the mortality rate of high-risk PUB in China are 15.6%, 1.8% and 0.5%, respectively.

语种英语
WOS记录号WOS:000328152800002
项目编号2012ZX09303011-002 ; 81270539
资助机构National Key Scientific and Technological Project ; National Natural Science Foundation of China ; AstraZeneca
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67584
专题北京大学第三临床医学院_消化科
作者单位1.Jinhua Municipal Cent Hosp, Dept Gastroenterol, Jinhua, Peoples R China
2.Second Mil Med Univ, Changhai Hosp, Dept Gastroenterol, Shanghai 200433, Peoples R China
3.Fudan Univ, Huadong Hosp, Dept Gastroenterol, Shanghai 200433, Peoples R China
4.Fudan Univ, Zhongshan Hosp, Dept Gastroenterol, Shanghai 200433, Peoples R China
5.Shanghai Jiao Tong Univ, Sch Med, Ruijin Hosp, Dept Gastroenterol, Shanghai 200030, Peoples R China
6.Third Mil Med Univ, Xinqiao Hosp, Dept Gastroenterol, Chongqing, Peoples R China
7.Third Mil Med Univ, Southwest Hosp, Dept Gastroenterol, Chongqing, Peoples R China
8.Third Mil Med Univ, Daping Hosp, Dept Gastroenterol, Chongqing, Peoples R China
9.Guangdong Gen Hosp, Dept Gastroenterol, Guangzhou, Guangdong, Peoples R China
10.Sun Yat Sen Univ, Affiliated Hosp 1, Dept Gastroenterol, Guangzhou 510275, Guangdong, Peoples R China
11.Southern Med Univ, Nanfang Hosp, Dept Gastroenterol, Guangzhou, Guangdong, Peoples R China
12.Jilin Univ, China Japan Union Hosp, Dept Gastroenterol, Changchun 130023, Jilin Province, Peoples R China
13.Wenzhou Med Coll, Affiliated Hosp 2, Dept Gastroenterol, Wenzhou, Peoples R China
14.Taizhou Hosp Zhejiang Prov, Dept Gastroenterol, Linhai, Zhejiang, Peoples R China
15.Zhejiang Univ, Affiliated Hosp 1, Dept Gastroenterol, Hangzhou, Zhejiang, Peoples R China
16.Capital Med Univ, Beijing Friendship Hosp, Dept Gastroenterol, Xiamen, Fujian Province, Peoples R China
17.Peking Univ, Hosp 3, Dept Gastroenterol, Xiamen, Fujian Province, Peoples R China
18.Peking Univ, Hosp 1, Dept Gastroenterol, Xiamen, Fujian Province, Peoples R China
19.Xiamen Univ, Affiliated Hosp 1, Dept Gastroenterol, Xiamen, Fujian Province, Peoples R China
20.Lanzhou Univ, Hosp 2, Dept Gastroenterol, Lanzhou 730000, Gansu, Peoples R China
21.Huazhong Univ Sci & Technol, Tongji Hosp, Dept Gastroenterol, Wuhan 430074, Hubei Province, Peoples R China
22.Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Gastroenterol, Wuhan, Hubei Province, Peoples R China
23.Nanchang Univ, Affiliated Hosp 1, Dept Gastroenterol, Nanchang, Jiangxi, Peoples R China
24.Fourth Mil Med Univ, Xijing Hosp Digest Dis, Dept Gastroenterol, Xian 710032, Shaanxi Provinc, Peoples R China
推荐引用方式
GB/T 7714
Bai, Yu,Du, Yi Qi,Wang, Dong,et al. Peptic ulcer bleeding in China: A multicenter endoscopic survey of 1006 patients[J]. JOURNAL OF DIGESTIVE DISEASES,2014,15(1):5-11.
APA Bai, Yu.,Du, Yi Qi.,Wang, Dong.,Zou, Duo Wu.,Jin, Zhen Dong.,...&Chinese Peptic Ulcer.(2014).Peptic ulcer bleeding in China: A multicenter endoscopic survey of 1006 patients.JOURNAL OF DIGESTIVE DISEASES,15(1),5-11.
MLA Bai, Yu,et al."Peptic ulcer bleeding in China: A multicenter endoscopic survey of 1006 patients".JOURNAL OF DIGESTIVE DISEASES 15.1(2014):5-11.
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