IR@PKUHSC  > 北京大学第一临床医学院  > 皮肤性病科
学科主题临床医学
Nickel-elicited systemic contact dermatitis - A report of 20 cases and a review of the literature
Dou, X; Liu, LL; Zhu, XJ
关键词nickel allergic contact dermatitis systemic contact dermatitis eczema
刊名CONTACT DERMATITIS
2003-03-01
48期:3页:126-129
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Allergy ; Dermatology
研究领域[WOS]Allergy ; Dermatology
关键词[WOS]FLARE-UP REACTIONS ; IN-VITRO ; ALLERGY
英文摘要

20 patients with systemic contact dermatitis due to nickel are described. Of these patients, 15 were female and 5 were male. Their mean age was 24.8 years (16-51 years). All had experienced contact dermatitis in the umbilical area due to continual contact with metal belt-buckles or buttons. Then, with long- or short-term aggravation of such periumbilical dermatitis, commonly in summer, lesions spread to other sites such as the side of the neck, the flexures of the extremities, etc. All patients showed a positive patch test to nickel sulphate (2.5% in petrolatum) and the dimethylglyoxime test demonstrated the presence of free nickel on metal buttons or belt-buckles. Punch biopsies performed in 7 patients showed subacute dermatitis. After avoidance of continual exposure to objects containing nickel and foods rich in nickel, as well as treatment with oral antihistamines and topical corticosteroids, all patients improved or cleared. It has been reported that nickel can cause systemic contact dermatitis by some internal systemic route, such as oral intake, transfusion, inhalation, implantation of metal medical devices, etc. In our patients, we found that continual local skin contact could also elicit systemic contact dermatitis.

语种英语
WOS记录号WOS:000182943700002
引用统计
被引频次:26[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67591
专题北京大学第一临床医学院_皮肤性病科
作者单位Peking Univ First Hosp, Dept Dermatol, Beijing 100034, Peoples R China
推荐引用方式
GB/T 7714
Dou, X,Liu, LL,Zhu, XJ. Nickel-elicited systemic contact dermatitis - A report of 20 cases and a review of the literature[J]. CONTACT DERMATITIS,2003,48(3):126-129.
APA Dou, X,Liu, LL,&Zhu, XJ.(2003).Nickel-elicited systemic contact dermatitis - A report of 20 cases and a review of the literature.CONTACT DERMATITIS,48(3),126-129.
MLA Dou, X,et al."Nickel-elicited systemic contact dermatitis - A report of 20 cases and a review of the literature".CONTACT DERMATITIS 48.3(2003):126-129.
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