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学科主题: 临床医学
题名:
Nickel-elicited systemic contact dermatitis - A report of 20 cases and a review of the literature
作者: Dou, X; Liu, LL; Zhu, XJ
关键词: nickel ; allergic contact dermatitis ; systemic contact dermatitis ; eczema
刊名: CONTACT DERMATITIS
发表日期: 2003-03-01
卷: 48, 期:3, 页:126-129
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Allergy ; Dermatology
研究领域[WOS]: Allergy ; Dermatology
关键词[WOS]: FLARE-UP REACTIONS ; IN-VITRO ; ALLERGY
英文摘要:

20 patients with systemic contact dermatitis due to nickel are described. Of these patients, 15 were female and 5 were male. Their mean age was 24.8 years (16-51 years). All had experienced contact dermatitis in the umbilical area due to continual contact with metal belt-buckles or buttons. Then, with long- or short-term aggravation of such periumbilical dermatitis, commonly in summer, lesions spread to other sites such as the side of the neck, the flexures of the extremities, etc. All patients showed a positive patch test to nickel sulphate (2.5% in petrolatum) and the dimethylglyoxime test demonstrated the presence of free nickel on metal buttons or belt-buckles. Punch biopsies performed in 7 patients showed subacute dermatitis. After avoidance of continual exposure to objects containing nickel and foods rich in nickel, as well as treatment with oral antihistamines and topical corticosteroids, all patients improved or cleared. It has been reported that nickel can cause systemic contact dermatitis by some internal systemic route, such as oral intake, transfusion, inhalation, implantation of metal medical devices, etc. In our patients, we found that continual local skin contact could also elicit systemic contact dermatitis.

语种: 英语
WOS记录号: WOS:000182943700002
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67591
Appears in Collections:北京大学第一临床医学院_皮肤性病科_期刊论文

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作者单位: Peking Univ First Hosp, Dept Dermatol, Beijing 100034, Peoples R China

Recommended Citation:
Dou, X,Liu, LL,Zhu, XJ. Nickel-elicited systemic contact dermatitis - A report of 20 cases and a review of the literature[J]. CONTACT DERMATITIS,2003,48(3):126-129.
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