北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 基础医学院  > 北京大学衰老研究中心  > 期刊论文
学科主题: 基础医学
题名:
HuR and post-transcriptional regulation in vascular aging
作者: Wang WenGong
关键词: HuR ; mRNA turnover ; translation ; cell senescence ; vascular aging
刊名: SCIENCE CHINA-LIFE SCIENCES
发表日期: 2014-08-01
DOI: 10.1007/s11427-014-4706-2
卷: 57, 期:8, 页:863-866
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Biology
研究领域[WOS]: Life Sciences & Biomedicine - Other Topics
关键词[WOS]: BINDING PROTEIN HUR ; P16(INK4) MESSENGER-RNA ; REPLICATIVE SENESCENCE ; ENDOTHELIAL-CELLS ; 3&prime ; -UNTRANSLATED REGION ; EXPRESSION ; GROWTH ; SIRT1 ; PHOSPHORYLATION ; PROLIFERATION
英文摘要:

HuR (ELAV11 (embryonic lethal, abnormal vision)-like 1), a ubiquitously expressed member of the ELAV-like RNA-binding protein family, has been shown to regulate the stability and translation of mRNAs that encode factors regulating cellular senescence, thereby impacting on aging. In this review, we discuss the current knowledge of HuR′s role in vascular cell senescence and vascular aging.

语种: 英语
所属项目编号: 81230008 ; 91339114 ; B07001
项目资助者: National Natural Science Foundation of China ; 111 project of Ministry of Education of China
WOS记录号: WOS:000340468700017
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67595
Appears in Collections:基础医学院_北京大学衰老研究中心_期刊论文

Files in This Item:
File Name/ File Size Content Type Version Access License
art%3A10.1007%2Fs11427-014-4706-2.pdf(435KB)期刊论文作者接受稿限制开放 联系获取全文

作者单位: Peking Univ, Hlth Sci Ctr, Dept Biochem & Mol Biol, Res Ctr Aging, Beijing 100191, Peoples R China

Recommended Citation:
Wang WenGong. HuR and post-transcriptional regulation in vascular aging[J]. SCIENCE CHINA-LIFE SCIENCES,2014,57(8):863-866.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Wang WenGong]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Wang WenGong]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace