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学科主题: 临床医学
题名:
Difference in left renal vein pressure: an indicator for free of reconstruction after ligation in retroperitoneal tumor patients
作者: Miao, Chengli1; Xiao, Mengmeng2; Li, Tengyan2; Liu, Gang2; Liu, Xing2; Kong, Yue3; Luo, Chenghua1
刊名: SCIENTIFIC REPORTS
发表日期: 2015-12-11
DOI: 10.1038/srep18126
卷: 5
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Multidisciplinary Sciences
研究领域[WOS]: Science & Technology - Other Topics
关键词[WOS]: INFERIOR VENA-CAVA ; MANAGEMENT ; DIAGNOSIS ; RESECTION
英文摘要:

We hypothesized that the left renal vein pressure difference (Delta P) before and after the ligation can serve as an objective indicator for free of reconstruction after resection of a retroperitoneal tumor with renal segment of inferior vena cava and right kidney. After established a model of left renal vein compression, 45 miniature pigs were operated on experimental procedures including renal segment of inferior vena cava resection, right nephrectomy, and left renal vein ligation. The Delta Ps of left renal vein before and after the ligation were measured. Safe Delta P variation without causing acute kidney injury was calculated using regression analysis. In human the safety range of Delta P before and after ligation of the left renal vein was calculated by diuretic response test. The safety range of Delta P in animals or human was 0-11.9 or 0-17.5 cm H2O, respectively. The renal function changed dramatically (p < 0.01), characterized by a significant increase in the rate of acute kidney injury when the Delta P was beyond the upper limit of the safety range. In conclusion, Delta P can predict free of reconstruction after resection of a retroperitoneal tumor with the renal segment of the inferior vena cava and the right kidney.

语种: 英语
所属项目编号: Z11110706730000 ; Z111107067311063
项目资助者: Capital Citizens Health Project of Cultivation
WOS记录号: WOS:000366183500001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67646
Appears in Collections:北京大学国际医院_期刊论文

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作者单位: 1.Peking Univ, Int Hosp, Dept Retroperitoneal Tumors Surg, Beijing 100871, Peoples R China
2.Peking Univ, Affiliated Hosp 9, Beijing Shijitan Hosp, Capital Med Univ,Dept Surg Oncol, Beijing 100871, Peoples R China
3.Peking Univ, Affiliated Hosp 9, Capital Med Univ, Beijing Shijitan Hosp,Ultrasound Dept, Beijing 100871, Peoples R China

Recommended Citation:
Miao, Chengli,Xiao, Mengmeng,Li, Tengyan,et al. Difference in left renal vein pressure: an indicator for free of reconstruction after ligation in retroperitoneal tumor patients[J]. SCIENTIFIC REPORTS,2015,5.
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