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学科主题口腔医学
Enhanced in vitro biocompatibility of ultrafine-grained biomedical NiTi alloy with microporous surface
Zheng, C. Y.1,2,3; Nie, F. L.1,2,3; Zheng, Y. F.1,2,3; Cheng, Y.3; Wei, S. C.4; Valiev, R. Z.5
关键词Ultrafine-grained alloy Surface modification Corrosion resistance Cytocompatibility
刊名APPLIED SURFACE SCIENCE
2011-08-15
DOI10.1016/j.apsusc.2011.05.105
257期:21页:9086-9093
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Physical ; Materials Science, Coatings & Films ; Physics, Applied ; Physics, Condensed Matter
资助者National High Technology Research and Development Program of China (863 Program) ; NSFC-RFBR ; National Natural Science Foundation of China ; Ministry of Science and Technology of China ; Research Funds for the Central Universities ; Program for New Century Excellent Talents in University ; National High Technology Research and Development Program of China (863 Program) ; NSFC-RFBR ; National Natural Science Foundation of China ; Ministry of Science and Technology of China ; Research Funds for the Central Universities ; Program for New Century Excellent Talents in University
研究领域[WOS]Chemistry ; Materials Science ; Physics
关键词[WOS]SEVERE PLASTIC-DEFORMATION ; TITANIUM ; CORROSION ; BIOACTIVITY ; RESISTANCE ; LAYER ; VIVO
英文摘要

Bulk ultrafine-grained Ni(50.8)Ti(49.2) alloy (UFG-NiTi) was successfully fabricated by equal-channel angular pressing (ECAP) technique in the present study, and to further improve its surface biocompatibility, surface modification techniques including sandblasting, acid etching and alkali treatment were employed to produce either irregularly roughened surface or microporous surface or hierarchical porous surface with bioactivity. The effect of the above surface treatments on the surface roughness, wettability, corrosion behavior, ion release, apatite forming ability and cytocompatibility of UFG-NiTi alloy were systematically investigated with the coarse-grained NiTi alloy as control. The pitting corrosion potential (E(pit)) was increased from 393 mV (SCE) to 704 mV (SCE) with sandblasting and further increased to 1539 mV (SCE) with following acid etching in HF/HNO(3) solution. All the above surface treatment increased the apatite forming ability of UFG-NiTi in varying degrees when soaked them in simulated body fluid (SBF). Meanwhile, both sandblasting and acid etching could promote the cytocompatibility for osteoblasts: sandblasting enhanced cell attachment and acid etching increased cell proliferation. The different corrosion behavior, apatite forming ability and cellular response of UFG-NiTi after different surface modifications are attributed to the topography and wettability of the resulting surface oxide layer. (C) 2011 Elsevier B.V. All rights reserved.

语种英语
所属项目编号2011AA030101 ; 2011AA030103 ; 31011120091 ; 51041004 ; 2007CB936103 ; PKUJC2009001 ; NCET-07-0033
资助者National High Technology Research and Development Program of China (863 Program) ; NSFC-RFBR ; National Natural Science Foundation of China ; Ministry of Science and Technology of China ; Research Funds for the Central Universities ; Program for New Century Excellent Talents in University ; National High Technology Research and Development Program of China (863 Program) ; NSFC-RFBR ; National Natural Science Foundation of China ; Ministry of Science and Technology of China ; Research Funds for the Central Universities ; Program for New Century Excellent Talents in University
WOS记录号WOS:000292539700053
引用统计
被引频次:16[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67705
专题北京大学口腔医学院
作者单位1.Peking Univ, Coll Engn, Dept Adv Mat & Nanotechnol, Beijing 100871, Peoples R China
2.Peking Univ, Coll Engn, State Key Lab Turbulence & Complex Syst, Beijing 100871, Peoples R China
3.Peking Univ, Ctr Biomed Mat & Tissue Engn, Acad Adv Interdisciplinary Studies, Beijing 100871, Peoples R China
4.Peking Univ, Sch Stomatol, Dept Oral & Maxillofacial Surg, Beijing 100081, Peoples R China
5.Ufa State Aviat Tech Univ, Inst Phys Adv Mat, Ufa, Russia
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GB/T 7714
Zheng, C. Y.,Nie, F. L.,Zheng, Y. F.,et al. Enhanced in vitro biocompatibility of ultrafine-grained biomedical NiTi alloy with microporous surface[J]. APPLIED SURFACE SCIENCE,2011,257(21):9086-9093.
APA Zheng, C. Y.,Nie, F. L.,Zheng, Y. F.,Cheng, Y.,Wei, S. C.,&Valiev, R. Z..(2011).Enhanced in vitro biocompatibility of ultrafine-grained biomedical NiTi alloy with microporous surface.APPLIED SURFACE SCIENCE,257(21),9086-9093.
MLA Zheng, C. Y.,et al."Enhanced in vitro biocompatibility of ultrafine-grained biomedical NiTi alloy with microporous surface".APPLIED SURFACE SCIENCE 257.21(2011):9086-9093.
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