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学科主题: 口腔医学
题名:
Enhanced in vitro biocompatibility of ultrafine-grained biomedical NiTi alloy with microporous surface
作者: Zheng, C. Y.1,2,3; Nie, F. L.1,2,3; Zheng, Y. F.1,2,3; Cheng, Y.3; Wei, S. C.4; Valiev, R. Z.5
关键词: Ultrafine-grained alloy ; Surface modification ; Corrosion resistance ; Cytocompatibility
刊名: APPLIED SURFACE SCIENCE
发表日期: 2011-08-15
DOI: 10.1016/j.apsusc.2011.05.105
卷: 257, 期:21, 页:9086-9093
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Physical ; Materials Science, Coatings & Films ; Physics, Applied ; Physics, Condensed Matter
研究领域[WOS]: Chemistry ; Materials Science ; Physics
关键词[WOS]: SEVERE PLASTIC-DEFORMATION ; TITANIUM ; CORROSION ; BIOACTIVITY ; RESISTANCE ; LAYER ; VIVO
英文摘要:

Bulk ultrafine-grained Ni(50.8)Ti(49.2) alloy (UFG-NiTi) was successfully fabricated by equal-channel angular pressing (ECAP) technique in the present study, and to further improve its surface biocompatibility, surface modification techniques including sandblasting, acid etching and alkali treatment were employed to produce either irregularly roughened surface or microporous surface or hierarchical porous surface with bioactivity. The effect of the above surface treatments on the surface roughness, wettability, corrosion behavior, ion release, apatite forming ability and cytocompatibility of UFG-NiTi alloy were systematically investigated with the coarse-grained NiTi alloy as control. The pitting corrosion potential (E(pit)) was increased from 393 mV (SCE) to 704 mV (SCE) with sandblasting and further increased to 1539 mV (SCE) with following acid etching in HF/HNO(3) solution. All the above surface treatment increased the apatite forming ability of UFG-NiTi in varying degrees when soaked them in simulated body fluid (SBF). Meanwhile, both sandblasting and acid etching could promote the cytocompatibility for osteoblasts: sandblasting enhanced cell attachment and acid etching increased cell proliferation. The different corrosion behavior, apatite forming ability and cellular response of UFG-NiTi after different surface modifications are attributed to the topography and wettability of the resulting surface oxide layer. (C) 2011 Elsevier B.V. All rights reserved.

语种: 英语
所属项目编号: 2011AA030101 ; 2011AA030103 ; 31011120091 ; 51041004 ; 2007CB936103 ; PKUJC2009001 ; NCET-07-0033
项目资助者: National High Technology Research and Development Program of China (863 Program) ; NSFC-RFBR ; National Natural Science Foundation of China ; Ministry of Science and Technology of China ; Research Funds for the Central Universities ; Program for New Century Excellent Talents in University
WOS记录号: WOS:000292539700053
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67705
Appears in Collections:北京大学口腔医学院_期刊论文

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作者单位: 1.Peking Univ, Coll Engn, Dept Adv Mat & Nanotechnol, Beijing 100871, Peoples R China
2.Peking Univ, Coll Engn, State Key Lab Turbulence & Complex Syst, Beijing 100871, Peoples R China
3.Peking Univ, Ctr Biomed Mat & Tissue Engn, Acad Adv Interdisciplinary Studies, Beijing 100871, Peoples R China
4.Peking Univ, Sch Stomatol, Dept Oral & Maxillofacial Surg, Beijing 100081, Peoples R China
5.Ufa State Aviat Tech Univ, Inst Phys Adv Mat, Ufa, Russia

Recommended Citation:
Zheng, C. Y.,Nie, F. L.,Zheng, Y. F.,et al. Enhanced in vitro biocompatibility of ultrafine-grained biomedical NiTi alloy with microporous surface[J]. APPLIED SURFACE SCIENCE,2011,257(21):9086-9093.
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