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学科主题临床医学
Characteristics of abnormal menstrual cycle and polycystic ovary syndrome in community and hospital populations
Ma Yan-min2; Li Rong; Qiao Jie1; Zhang Xiao-wei3; Wang Shu-yu4; Zhang Qiu-fang; Li Li; Tu Bin-bin; Zhang Xue
关键词polycystic ovary syndrome menstrual cycle community hospital
刊名CHINESE MEDICAL JOURNAL
2010-08-20
DOI10.3760/cma.j.issn.0366-6999.2010.16.005
123期:16页:2185-2189
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal
研究领域[WOS]General & Internal Medicine
关键词[WOS]DIAGNOSTIC-CRITERIA ; ROTTERDAM CRITERIA ; PREVALENCE ; WOMEN ; PCOS ; CONSENSUS ; CANCER
英文摘要

Background Polycystic ovary syndrome (PCOS) is considered to be the most common endocrine disorder in women of reproductive age The involvement of an abnormal menstrual cycle in the etiology of PCOS remains unclear. We aimed to analyze the characteristics of abnormal menstrual cycles and their association with PCOS in community and hospital patient populations

Methods Women with PCOS identified from 2111 permanent female residents in the community of Beijing and 506 outpatients obtained from the reproductive clinic of Peking University Third Hospital were recruited for this study, comprising the PCOS community group and the PCOS hospital group, respectively Each group was further divided into four subgroups according to the length of menstrual cycles: <21 days, 21-34 days, 35-60 days; and >60 days. Women in each group were interviewed using a questionnaire to assess factors including age, age of menarche, menstrual cycle history, related family history, and modified Ferriman-Gallwey (mF-G) score. All women received transvaginal ultrasound scan and had fasting blood samples taken for endocrine evaluation. A two-tailed P value of <0.05 was considered significant

Results In the community population, the prevalence of abnormal menstrual cycle was 27.19% (574/2111). The prevalence of PCOS in the community was 6 11% (129/2111) according to Rotterdam criteria. In the community group, the most common menstrual cycle length was 35-60 days, whereas for the hospital group, it was >60 days. In both the community and hospital groups, the most common phenotype of PCOS was that of Oligo/amenorrhea+PCO+ hyperandrogenism (HA) (O+P+H) (P=0.000) With increasing cycle length of 35-60 days to >60 days, the percentages of Oligo/amenorrhea+PCO (O+P) and O+P+H were found to significantly decrease in the community group and significantly increase in the hospital group (P=0 000 for each). In the hospital group, as the menstrual cycle length increased from 35-60 days to >60 days, the rate of spontaneous abortion increased significantly (P=0.000), meanwhile the rate of poorly-secreted endometrium and abnormal endometrial hyperplasia increased significantly (P=0 000).

Conclusions The prevalence of PCOS in the Beijing community of women was 6 11%. Oligo/amenorrhea was the most common type of abnormal menstrual cycle and may be an indicator for PCOS and endometrial lesions. Gynecologists should seek relevant medical information from women in the community to promptly diagnose PCOS and then follow up patients for potential development of subsequent complications.

语种英语
WOS记录号WOS:000281488300005
项目编号2007BA104B00 ; 30825038
资助机构Ministry of Science &amp ; Technology of China ; National Science Fund for Outstanding Youths
引用统计
被引频次:14[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67728
专题北京大学第三临床医学院_生殖医学中心
作者单位1.Peking Univ, Hosp 3, Dept Obstet & Gynecol, Reprod Med Ctr, Beijing 100191, Peoples R China
2.Capital Med Univ, Beijing Obstet & Gynecol Hosp Affiliated, Reprod Med Ctr, Beijing 100026, Peoples R China
3.Peking Univ, Hosp 3, Dept Genet, Reprod Med Ctr, Beijing 100191, Peoples R China
4.Capital Med Univ, Reprod Med Ctr, Beijing Obstet & Gynecol Hosp Affiliated, Beijing 100026, Peoples R China
推荐引用方式
GB/T 7714
Ma Yan-min,Li Rong,Qiao Jie,et al. Characteristics of abnormal menstrual cycle and polycystic ovary syndrome in community and hospital populations[J]. CHINESE MEDICAL JOURNAL,2010,123(16):2185-2189.
APA Ma Yan-min.,Li Rong.,Qiao Jie.,Zhang Xiao-wei.,Wang Shu-yu.,...&Zhang Xue.(2010).Characteristics of abnormal menstrual cycle and polycystic ovary syndrome in community and hospital populations.CHINESE MEDICAL JOURNAL,123(16),2185-2189.
MLA Ma Yan-min,et al."Characteristics of abnormal menstrual cycle and polycystic ovary syndrome in community and hospital populations".CHINESE MEDICAL JOURNAL 123.16(2010):2185-2189.
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