IR@PKUHSC  > 北京大学第二临床医学院
学科主题临床医学
Societal Costs of Rheumatoid Arthritis in China: A Hospital-Based Cross-Sectional Study
Xu, Chuanhui1; Wang, Xiuru1,2; Mu, Rong1; Yang, Li3; Zhang, Ye3; Han, Shuling2; Li, Xiaofeng4; Wang, Yongfu5; Wang, Guochun6; Zhu, Ping7; Jin, Hongtao8; Sun, Lin9; Chen, Haiying10; Cui, Liufu11; Zhang, Zhuoli12; Li, Zhenbin13; Li, Junfang14; Zhang, Fengxiao15; Lin, Jinying16; Liu, Xiaomin17; Hu, Shaoxian18; Yang, Xiuyan19; Lai, Bei20; Li, Xingfu21; Wang, Xiaoyuan22; Su, Yin1; Li, Zhanguo1
刊名ARTHRITIS CARE & RESEARCH
2014-04-01
DOI10.1002/acr.22160
66期:4页:523-531
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Rheumatology
资助者National Basic Research Program of China (973 program) ; National Natural Science Foundation of China ; National Basic Research Program of China (973 program) ; National Natural Science Foundation of China
研究领域[WOS]Rheumatology
关键词[WOS]ANKYLOSING-SPONDYLITIS ; ECONOMIC BURDEN ; MEDICAL COSTS ; OF-ILLNESS ; HONG-KONG ; PREVALENCE ; DISEASE ; CARE ; PREDICTORS ; MANAGEMENT
英文摘要

ObjectiveTo estimate the annual direct and indirect costs of rheumatoid arthritis (RA) in China and identify the predictors for cost of illness.

MethodsA cross-sectional study of cost of illness from the societal perspective was conducted on 829 patients with RA in 21 tertiary care hospitals in China between July 2009 and December 2010. Data on demographics, clinical variables, and components of costs were collected by physician interview. Costs were represented in 2009 US dollars using purchasing power parity estimates. Univariate and multivariate linear regression analyses were performed to identify the predictors for cost of illness.

ResultsThe mean SD total cost of RA in China was $3,826 +/- $5,659 per patient-year, given a gross domestic product per capita of $6,798 in China in 2009. Direct costs and indirect costs comprised 90.0% and 10.0% of the total costs, respectively. Drug expense represented approximately half of the total costs, dominated by biologic agents (48.2%) and disease-modifying antirheumatic drugs (23.5%). Additionally, the cost of extracted herbal drugs and traditional Chinese medicine comprised approximate to 17.6% of the drug expense. Higher education level, noninsured status, longer disease duration, more extraarticular manifestations, and higher Health Assessment Questionnaire score independently predicted higher total costs.

ConclusionOur results provide the first study of costs of RA in China. This study not only demonstrates the economic burden of RA, but also identifies the predictors that could be interventional factors to reduce the societal costs of RA in China.

语种英语
所属项目编号2010CB529104 ; 81072401
资助者National Basic Research Program of China (973 program) ; National Natural Science Foundation of China ; National Basic Research Program of China (973 program) ; National Natural Science Foundation of China
WOS记录号WOS:000333380400004
引用统计
被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67758
专题北京大学第二临床医学院
作者单位1.China Japan Friendship Hosp, Beijing, Peoples R China
2.Peking Univ, Hosp 3, Beijing 100871, Peoples R China
3.Peking Univ, Hosp 1, Beijing 100871, Peoples R China
4.Peking Univ, Shougang Hosp, Beijing 100871, Peoples R China
5.Peking Univ, Hlth Sci Ctr, Beijing 100871, Peoples R China
6.Baotou Med Coll, Affiliated Hosp 1, Baotou, Peoples R China
7.Peking Univ, Peoples Hosp, Hlth Sci Ctr, Beijing 100871, Peoples R China
8.Shanxi Med Univ, Affiliated Hosp 2, Taiyuan, Peoples R China
9.Fourth Mil Med Univ, Xijing Hosp, Xian 710032, Peoples R China
10.Hebei Med Univ, Affiliated Hosp 2, Shijiazhuang, Peoples R China
11.Hebei Med Univ, Affiliated Hosp 3, Shijiazhuang, Peoples R China
12.North China Coal Med Univ, Affiliated Kailuan Hosp, Tangshan, Hebei, Peoples R China
13.Bethune Int Peace Hosp PLA, Shijiazhuang, Peoples R China
14.Handan Cent Hosp, Handan, Peoples R China
15.Peoples Hosp Hebei Prov, Shijiazhuang, Peoples R China
16.Peoples Hosp Guangxi Zhuang Autonomous Reg, Nanning, Peoples R China
17.China Med Univ, Beijing Shunyi Hosp, Beijing, Peoples R China
18.Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Wuhan 430074, Peoples R China
19.Sun Yat Sen Univ, Affiliated Hosp 1, Guangzhou 510275, Guangdong, Peoples R China
20.Beijing Hosp, Beijing, Peoples R China
21.Shandong Univ, Qilu Hosp, Jinan 250100, Peoples R China
22.Lanzhou Univ, Affiliated Hosp 2, Lanzhou 730000, Peoples R China
推荐引用方式
GB/T 7714
Xu, Chuanhui,Wang, Xiuru,Mu, Rong,et al. Societal Costs of Rheumatoid Arthritis in China: A Hospital-Based Cross-Sectional Study[J]. ARTHRITIS CARE & RESEARCH,2014,66(4):523-531.
APA Xu, Chuanhui.,Wang, Xiuru.,Mu, Rong.,Yang, Li.,Zhang, Ye.,...&Li, Zhanguo.(2014).Societal Costs of Rheumatoid Arthritis in China: A Hospital-Based Cross-Sectional Study.ARTHRITIS CARE & RESEARCH,66(4),523-531.
MLA Xu, Chuanhui,et al."Societal Costs of Rheumatoid Arthritis in China: A Hospital-Based Cross-Sectional Study".ARTHRITIS CARE & RESEARCH 66.4(2014):523-531.
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