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学科主题: 药学
题名:
Comparative studies of saponins in 1-3-year-old main roots, fibrous roots, and rhizomes of Panax notoginseng, and identification of different parts and growth-year samples
作者: Jia, Xiu-Hong1; Wang, Chao-Qun1; Liu, Jin-Huai1,2; Li, Xiao-Wei3; Wang, Xuan1; Shang, Ming-Ying3; Cai, Shao-Qing3; Zhu, Shu4; Komatsu, Katsuko4
关键词: Panax notoginseng ; Growth year ; Different parts ; HPLC-DAD ; Ginsenosides/ notoginsenosides ; Quantitative analyses
刊名: JOURNAL OF NATURAL MEDICINES
发表日期: 2013-04-01
DOI: 10.1007/s11418-012-0691-6
卷: 67, 期:2, 页:339-349
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]: Pharmacology & Pharmacy
关键词[WOS]: CELLS ; METABOLISM ; GINSENG
英文摘要:

Notoginsenosides R-1, R-4, Fa, and K (N-R-1, N-R-4, N-Fa, and N-K), as well as ginsenosides Rg(1), Rb-1, Rd, Re, Rf, Rg(2) and Rh-1 (G-Rg(1), G-Rb-1, G-Rd, G-Re, G-Rf, G-Rg(2) and G-Rh-1) in 47 Notoginseng samples including 1-, 2- and 3-year-old main roots, rhizomes and fibrous roots of Panax notoginseng were determined by high-performance liquid chromatography-diode array detection method. Total contents (%) of the 11 saponins were 9.82-14.57 for 2-year old and 14.20-16.00 for 3-year-old rhizomes; 2.72-4.50 for 2-year-old and 1.98-4.92 for 3-year-old fibrous roots; 1.75-3.05 for 1-year-old whole roots; and 3.71-8.98 for 2-year-old and 7.03-11.23 for 3-year-old main roots. Contents of most saponins and total content of 11 saponins were in the order 3- > 2- > 1-year-old main root samples. G-Rf content, sum of G-Rf and G-Rh-1 were, respectively, 0.08-0.18 and 0.14-0.32 for 2- or 3-year-old rhizomes, and 0.01-0.07 and 0.03-0.10 for 2- or 3-year-old main roots. Combined contents of N-R-1, G-Rg(1) and G-Rb-1 were 5.78-9.37 in 3-year-old main roots, and 2.99-7.13 in 2-year-old main roots, of which nearly one-third of samples were lower than the limit (5 %) in the Chinese Pharmacopoeia. Those of 2- or 3-year-old fibrous roots (1.47-3.83) and 1-year-old whole roots (1.41-2.44) were much lower than the limit, and were considered not suitable for use as Notoginseng. Two-year-old main roots are not appropriate for collection as Notoginseng. Different parts and growth years of P. notoginseng can be identified from each another according to differences in saponin content.

语种: 英语
所属项目编号: 39970898 ; G1999054406 ; 2001BA701A55-3 ; 200707009
项目资助者: National Natural Science Foundation of China ; National 973 Program Foundation of China ; National New Drug Discovery and Modernization of Chinese Materia Medica Project ; TCM Research Projects of SATCM
WOS记录号: WOS:000316021400014
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67772
Appears in Collections:北京大学药学院_化学生物学系_期刊论文

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作者单位: 1.Peking Univ, Sch Pharmaceut Sci, Dept Biol Chem, Beijing 100191, Peoples R China
2.North China Pharmaceut Grp Corp, Drug R&D Ctr, Shijiazhuang 050015, Peoples R China
3.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
4.Toyama Univ, Div Pharmacognosy, Dept Med Resources, Inst Nat Med, Toyama 9300194, Japan

Recommended Citation:
Jia, Xiu-Hong,Wang, Chao-Qun,Liu, Jin-Huai,et al. Comparative studies of saponins in 1-3-year-old main roots, fibrous roots, and rhizomes of Panax notoginseng, and identification of different parts and growth-year samples[J]. JOURNAL OF NATURAL MEDICINES,2013,67(2):339-349.
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