IR@PKUHSC  > 北京大学第二临床医学院  > 心血管内科
学科主题临床医学
Feasibility of diagnosing unstable plaque in patients with acute coronary syndrome using iMap-IVUS
Liu, Jian; Wang, Zhao; Wang, Wei-min; Li, Qi; Ma, Yu-liang; Liu, Chuan-fen; Lu, Ming-yu; Zhao, Hong
关键词Acute coronary syndrome Intravascular ultrasound Unstable plaque
刊名JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B
2015-11-01
DOI10.1631/jzus.B1500206
16期:11页:924-930
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Medicine, Research & Experimental
研究领域[WOS]Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Research & Experimental Medicine
关键词[WOS]ATHEROSCLEROTIC PLAQUE ; VIRTUAL HISTOLOGY ; ULTRASOUND ; COMPONENTS
英文摘要

To compare the plaque composition between stable and unstable plaques, characterize unstable plaque by using iMap-intravascular ultrasound (IVUS), and quantify the diagnostic criteria for unstable plaque.

Thirty-three acute coronary syndrome (ACS) patients who had undergone coronary angiography and IVUS from February 19, 2014 to December 19, 2014 at Peking University People′s Hospital were enrolled in the study. Baseline data were collected. The patients were divided into two groups according to their gray-scale IVUS imaging, stable plaque and unstable plaque. A difference-in-difference evaluation was performed using the baseline data and off-line iMap imaging results between the two groups. A receiver operating characteristic (ROC) curve was constructed to obtain the optimal cut-off value to diagnose unstable plaque.

Percentages of fibrotic and necrotic tissues, absolute values of lipidic, necrotic, and calcified tissues, and plaque burden were independent predictors for unstable plaque. Absolute necrotic area was the best predictor and exhibited the highest diagnostic value for plaque vulnerability (area under the curve (AUC)=0.806, P=0.000, 95% CI (0.718, 0.894)). The cut-off score for predicting unstable plaque was 4.0 mm(2).

This study attempted to propose a cut-off value based on absolute necrotic area using iMap-IVUS to predict plaque vulnerability in patients with ACS. This score might provide a valuable reference for diagnosing unstable plaque.

语种英语
WOS记录号WOS:000364941800004
项目编号2014-2-4085
资助机构Capital Health Research and Development of Special, China
引用统计
被引频次:2[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67792
专题北京大学第二临床医学院_心血管内科
北京大学医学部管理机构_教育处
北京大学基础医学院
北京大学口腔医学院_口腔预防保健科
作者单位Peking Univ, Peoples Hosp, Dept Cardiol, Beijing 100044, Peoples R China
推荐引用方式
GB/T 7714
Liu, Jian,Wang, Zhao,Wang, Wei-min,et al. Feasibility of diagnosing unstable plaque in patients with acute coronary syndrome using iMap-IVUS[J]. JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B,2015,16(11):924-930.
APA Liu, Jian.,Wang, Zhao.,Wang, Wei-min.,Li, Qi.,Ma, Yu-liang.,...&Zhao, Hong.(2015).Feasibility of diagnosing unstable plaque in patients with acute coronary syndrome using iMap-IVUS.JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B,16(11),924-930.
MLA Liu, Jian,et al."Feasibility of diagnosing unstable plaque in patients with acute coronary syndrome using iMap-IVUS".JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B 16.11(2015):924-930.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Liu, Jian]的文章
[Wang, Zhao]的文章
[Wang, Wei-min]的文章
百度学术
百度学术中相似的文章
[Liu, Jian]的文章
[Wang, Zhao]的文章
[Wang, Wei-min]的文章
必应学术
必应学术中相似的文章
[Liu, Jian]的文章
[Wang, Zhao]的文章
[Wang, Wei-min]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。