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学科主题: 药学
题名:
Lignans from the roots and rhizomes of Clematis manshurica
作者: Shi, She-Po; Jiang, Dan; Dong, Cai-Xia; Tu, Peng-Fei
关键词: Clematis manshurica Rpur. ; lignans ; clemomanshurinane A ; clemomanshurinane B ; COX-2
刊名: ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
发表日期: 2006-10-01
卷: 61, 期:10, 页:1299-1303
收录类别: SCI ; IC
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Inorganic & Nuclear ; Chemistry, Organic
研究领域[WOS]: Chemistry
关键词[WOS]: GLUCOSIDES ; CONSTITUENTS
英文摘要:

Two new lignans, clemomanshurinane A and B, along with ten known compounds have been isolated from the roots and rhizomes of Clematis manshurica. The structures were elucidated on the basis of their physicochemical and spectroscopic evidence. Clemomanshurinane A and B, (+)-dihydrode-hydrodiconiferyl alcohol and (+)-lariciresinol 4,4′-O-bis-beta-D-glucopyranoside indicated inhibitory effects on COX-2 at final concentration of 10(-5) mol/l, with the inhibition rates 65.8%, 71.8%, 53.3%, and 60.3%, respectively.

语种: 英语
WOS记录号: WOS:000242481200018
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67803
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Peking Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Beijing 100083, Peoples R China
2.NE Normal Univ, Sch Life Sci, Changchun 130024, Peoples R China
3.Shanxi Coll Tradit Chinses Med, Sch Pharmaceut Sci, Xianyang 712046, Peoples R China

Recommended Citation:
Shi, She-Po,Jiang, Dan,Dong, Cai-Xia,et al. Lignans from the roots and rhizomes of Clematis manshurica[J]. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES,2006,61(10):1299-1303.
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