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学科主题: 药学
题名:
Microbial metabolism of artemisinin by Mucor polymorphosporus and Aspergillus niger
作者: Zhan, JX; Zhang, YX; Guo, HZ; Han, J; Ning, LL; Guo, DA
刊名: JOURNAL OF NATURAL PRODUCTS
发表日期: 2002-11-01
DOI: 10.1021/np020113r
卷: 65, 期:11, 页:1693-1695
收录类别: SCI ; IC
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]: Plant Sciences ; Pharmacology & Pharmacy
关键词[WOS]: MAMMALIAN METABOLISM ; ANTIMALARIAL DRUG ; TRANSFORMATION ; ARTEETHER ; ANALOGS
英文摘要:

Artemisinin (1) was transformed by Mucor polymorphosporus and Aspergillus niger. Five products were identified as 9beta-hydroxyartemisinin (2), 3beta-hydroxyartemisinin (3), deoxyartemisinin (4), 3beta-hydroxydeoxyartemisinin (5), and 1alpha-hydroxydeoxyartemisinin (6). Products 2, 3, and 6 are new compounds.

语种: 英语
WOS记录号: WOS:000179394400037
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67818
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China
2.E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China

Recommended Citation:
Zhan, JX,Zhang, YX,Guo, HZ,et al. Microbial metabolism of artemisinin by Mucor polymorphosporus and Aspergillus niger[J]. JOURNAL OF NATURAL PRODUCTS,2002,65(11):1693-1695.
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