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学科主题: 临床医学
题名:
The Frequency and Treatment of Dural Tears and Cerebrospinal Fluid Leakage in 266 Patients With Thoracic Myelopathy Caused by Ossification of the Ligamentum Flavum
作者: Sun, Xinzhi; Sun, Chuiguo; Liu, Xiaoguang; Liu, Zhongjun; Qi, Qiang; Guo, Zhaoqing; Leng, Huijie; Chen, Zhongqiang
关键词: ossification of the ligamentum flavum ; dural tears ; dural ossification ; cerebrospinal fluid leakage ; complication
刊名: SPINE
发表日期: 2012-05-20
DOI: 10.1097/BRS.0b013e31824586a8
卷: 37, 期:12, 页:E702-E707
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology ; Orthopedics
研究领域[WOS]: Neurosciences & Neurology ; Orthopedics
关键词[WOS]: POSTERIOR LONGITUDINAL LIGAMENT ; SURGICAL-TREATMENT ; LUMBAR SPINE ; FOLLOW-UP ; MANAGEMENT ; SURGERY ; LAMINECTOMY ; POPULATION ; SECONDARY
英文摘要:

Study Design. Retrospective review.

Objective. To perform a single-institution analysis of incidence, treatment, and clinical outcome in patients with thoracic ossification of the ligamentum flavum (OLF) who experienced dural tears and cerebrospinal fluid (CSF) leakage.

Summary of Background Data. There is a paucity of clinical reports focusing on dural tears and CSF leakage after thoracic OLF surgery. Because dural adhesion and dural ossification are common features of thoracic OLF, the incidence of CSF leakage in OLF patients is high and represents a significant clinical challenge.

Methods. A total of 266 patients with thoracic OLF were admitted to our hospital from 1995 to 2011. Each patient′s medical records were reviewed to identify cases of dural tears and CSF leakage. Information on therapeutic strategy used to repair the dural tears and complications related to CSF leakage was extracted.

Results. The incidence of dural tears and CSF leakage in OLF patients was 32% (85/266). The incidence of dural ossification was 25.2%. The dural tears were repaired with a range of materials, including gelatin sponge, muscle/fascia, artificial dura, silk suture, and fibrin glue. The intraoperative repair procedure did not resolve CSF leakage in 65 cases, and 16 of those cases experienced complications related to the continued CSF leakage, including CSF pseudocyst, wound dehiscence, and meningitis. Fifty-eight patients with CSF leakage were eventually cured by a series of comprehensive treatments, which included prone position, continuous pressure by sandbag, ultrasound-guided puncture, and aspiration. Only 7 patients required reoperation.

Conclusion. Dural ossification was the main reason for dural tears. In all, 78 of the 85 patients with CSF leakage or dural tear were successfully cured. The success rate was 91.8%, which indicated that a series of comprehensive treatments was an effective strategy to treat these patients.

语种: 英语
WOS记录号: WOS:000304364800003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/67864
Appears in Collections:北京大学第三临床医学院_骨科_期刊论文

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作者单位: Peking Univ, Hosp 3, Dept Orthopaed, Beijing 100191, Peoples R China

Recommended Citation:
Sun, Xinzhi,Sun, Chuiguo,Liu, Xiaoguang,et al. The Frequency and Treatment of Dural Tears and Cerebrospinal Fluid Leakage in 266 Patients With Thoracic Myelopathy Caused by Ossification of the Ligamentum Flavum[J]. SPINE,2012,37(12):E702-E707.
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