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学科主题口腔医学
Effects of a mandibular repositioner on obstructive sleep apnea
Liu, YH; Zeng, XL; Fu, MK; Huang, XZ; Lowe, AA
刊名AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS
2000-09-01
DOI10.1067/mod.2000.104831
118期:3页:248-256
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Dentistry, Oral Surgery & Medicine
研究领域[WOS]Dentistry, Oral Surgery & Medicine
关键词[WOS]POSITIVE AIRWAY PRESSURE ; ADVANCEMENT DEVICE ; MORPHOLOGY ; APPLIANCE ; UVULOPALATOPHARYNGOPLASTY ; PREDICTORS
英文摘要

The purpose of this study was to investigate the effects of a mandibular repositioner on airway, sleep, and respiratory variables in patients with obstructive sleep apnea, Twenty-two patients selected for this study were confirmed with a diagnosis of obstructive sleep apnea based on initial nocturnal polysomnography, The patients were fitted with a mandibular repositioner designed to hold the mandible anteroinferiorly. Six months later, an outcome polysomnographic study was undertaken for each patient with the appliance in place. Lateral cephalometric radiographs in the upright position were also obtained before and after 6 months of treatment, The respiratory disturbance index decreased in 21 of the 22 patients with the appliance in place, The mean respiratory disturbance index of the 22 patients decreased significantly from 40.3 to 11.7 events per hour (P <.01), Some 59.1% of subjects were considered a treatment success with follow-up respiratory disturbance index < 10 events per hour. The mean minimum blood oxygen saturation level during sleep also improved significantly from 73.4% to 81.3% (P <.01). The mandibular repositioner was constructed to position the mandible at 75% of the maximal mandibular advancement and with a 7 mm opening between the upper and lower incisors, and no aberrant effect on temporomandibular joint was noted. The retropalatal airway space increased and the cross-sectional area of the soft palate and the vertical distance of the hyoid bone to the mandibular plane decreased significantly, The tongue posture became significantly flatter. A significant linear correlation was found between the reduction in apnea index and specific craniofacial skeletal structures (length of anterior cranial base, mandibular plane angle, and upper to lower facial height ratios, P <.05). Subjects with a smaller reduction in apnea index tended to have shorter anterior cranial bases, steeper mandibular planes, and smaller upper to lower facial height ratios. We conclude that a mandibular repositioner may be an effective treatment alternative for obstructive sleep apnea and that a reduction in the frequency of apneic episodes is mainly attributed to the effects of the appliance on oropharyngeal structures.

语种英语
WOS记录号WOS:000089330200003
引用统计
被引频次:44[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67890
专题北京大学口腔医学院_牙周科
作者单位1.Univ British Columbia, Dept Oral Hlth Sci, Fac Dent, Div Orthodont, Vancouver, BC V6T 1Z3, Canada
2.Beijing Med Univ, Sch Stomatol, Dept Orthodont, Beijing, Peoples R China
3.Chinese Union Med Univ, Beijing Union Hosp, Dept Med, Beijing, Peoples R China
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GB/T 7714
Liu, YH,Zeng, XL,Fu, MK,et al. Effects of a mandibular repositioner on obstructive sleep apnea[J]. AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS,2000,118(3):248-256.
APA Liu, YH,Zeng, XL,Fu, MK,Huang, XZ,&Lowe, AA.(2000).Effects of a mandibular repositioner on obstructive sleep apnea.AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS,118(3),248-256.
MLA Liu, YH,et al."Effects of a mandibular repositioner on obstructive sleep apnea".AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS 118.3(2000):248-256.
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