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学科主题临床医学
Current evidences on the XPG Asp1104His polymorphism and melanoma susceptibility: a meta-analysis based on case-control studies
Xu, Yuanzhi1; Jiao, Guangjun2; Wei, Li3,4; Wang, Ning3; Xue, Yajun1; Lan, Jin1; Wang, Yajie3; Liu, Chuan3; Lou, Meiqing1
关键词XPG Asp1104His Polymorphism Melanoma Meta-analysis
刊名MOLECULAR GENETICS AND GENOMICS
2015-02-01
DOI10.1007/s00438-014-0917-2
290期:1页:273-279
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Genetics & Heredity
资助者Shanghai Science and Technology Committee ; Shanghai Science and Technology Committee
研究领域[WOS]Biochemistry & Molecular Biology ; Genetics & Heredity
关键词[WOS]NUCLEOTIDE EXCISION-REPAIR ; DNA-REPAIR ; CUTANEOUS MELANOMA ; GENETIC POLYMORPHISMS ; RISK ; CANCER ; ASSOCIATION ; EXPRESSION ; PROGNOSIS ; UPDATE
英文摘要

Previous studies evaluating the association between the XPG Asp1104His polymorphism and melanoma susceptibility remained controversial. To draw a more precise estimation of the relationship, a total of eight published case-control studies containing 5,212 cases and 7,045 controls were included for meta-analysis. Overall, a significant association was found between the XPG Asp1104His polymorphism and melanoma susceptibility for the dominant model (OR = 2.42, 95 % CI = 2.26-2.60). In subgroup analysis by source of control, there was an obvious association was found among Population-based subgroup for the dominant model CC+GC vs GG (OR 2.51, 95 % CI 2.28-2.77), among the Hospital-based subgroup, an obvious association was also found for the dominant model CC+GC vs GG (OR 2.34, 95 % CI 2.12-2.58). This meta-analysis suggested that the XPG Asp1104His polymorphism was a risk factor for melanoma susceptibility.

语种英语
所属项目编号12JC1406202 ; 13DZ1942807
资助者Shanghai Science and Technology Committee ; Shanghai Science and Technology Committee
WOS记录号WOS:000348923900021
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/67920
专题北京大学第二临床医学院_骨肿瘤科
作者单位1.Shanghai Jiao Tong Univ, Sch Med, Shanghai Peoples Hosp 1, Dept Neurosurg, Shanghai 200080, Peoples R China
2.Peking Univ, Musculoskeletal Tumor Ctr, Peoples Hosp, Beijing 100871, Peoples R China
3.Second Mil Med Univ, Changhai Hosp, Dept Oncol, Shanghai 200433, Peoples R China
4.PLA, Hosp 401, Dept Oncol, Qingdao, Shandong, Peoples R China
推荐引用方式
GB/T 7714
Xu, Yuanzhi,Jiao, Guangjun,Wei, Li,et al. Current evidences on the XPG Asp1104His polymorphism and melanoma susceptibility: a meta-analysis based on case-control studies[J]. MOLECULAR GENETICS AND GENOMICS,2015,290(1):273-279.
APA Xu, Yuanzhi.,Jiao, Guangjun.,Wei, Li.,Wang, Ning.,Xue, Yajun.,...&Lou, Meiqing.(2015).Current evidences on the XPG Asp1104His polymorphism and melanoma susceptibility: a meta-analysis based on case-control studies.MOLECULAR GENETICS AND GENOMICS,290(1),273-279.
MLA Xu, Yuanzhi,et al."Current evidences on the XPG Asp1104His polymorphism and melanoma susceptibility: a meta-analysis based on case-control studies".MOLECULAR GENETICS AND GENOMICS 290.1(2015):273-279.
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