|Pattern of Drug Use and Depressive Symptoms among Amphetamine Type Stimulants Users in Beijing and Guangdong Province, China|
|Bao, Yan-ping1; Qiu, Yi1; Yan, Shi-yan1,2; Jia, Zhen-jun1; Li, Su-xia1; Lian, Zhi1; Mu, Yue1; Liu, Zhi-min1|
|收录类别||SCI ; SSCI|
|WOS标题词||Science & Technology|
|研究领域[WOS]||Science & Technology - Other Topics|
|关键词[WOS]||METHAMPHETAMINE USE ; NORTHERN THAILAND ; YOUNG-ADULTS ; ASSOCIATIONS ; DISORDERS ; MORBIDITY ; SMOKING ; ONSET ; MOOD|
Background: In recent years, amphetamine-type stimulants (ATS) have increased dramatically in East-south Asia, especially in China. Most ATS users suffered from psychosis comorbidity, and depression is the main syndrome in ATS users.
Methodology: A cross-sectional study of depressive symptoms and associated factors among ATS users was conducted in compulsory and voluntary drug detoxification and rehabilitation centers of Beijing and Guangdong Province from March, 2010 to August, 2010. Total 402 eligible participants were recruited and investigated by trained interviewers using a structured questionnaire, the depression was measured by the short 13-item Beck Depression Inventory (BDI-13). Multiple logistic regression was used to determine the impact of associated risk factors of depressive symptoms (%>= 8).
Principle Finding: The mean score of BDI-13 is 8.11, and 169 participants (42.04%) have depressive symptoms, including 106 (26.37%) with moderate and 63 (15.67%) with severe depressive symptoms. Higher dose of ATS use, history of ATS relapse were associated with moderate and severe depressive symptoms, the adjusted odds ratios (OR) was 2.62, (95% CI: 1.45-4.74) and 2.01 (95% CI: 1.18-3.42) respectively. The cessation of 12 months or more had less risk of depressive symptoms than the current users, the OR was 0.46 (95% CI: 0.24-0.91), and the ATS users reporting nicotine dependence and alcohol drinking had significantly more risk of depressive symptoms for 3.11 (1.83-5.28) and 2.22 (1.35-3.65) times than those without these behaviors.
Conclusions: Depressive symptoms co-occurred frequently among ATS users in China. The efforts that facilitate drug users′ attempts to stop using ATS use and relapse, quit cigarette smoking and stop alcohol drinking during the ATS treatment and management process should be supported as they may contribute to improving the mental health among this population.
|项目编号||2009CB522007 ; 2012BAI01B07 ; 2012ZX10001001 ; 81001265|
|资助机构||National Basic Research Program of China ; Twelfth Five-Year Program of the Chinese Ministry of Science and Technology ; National Natural Science Foundation of China|
|作者单位||1.Peking Univ, Natl Inst Drug Dependence, Beijing 100871, Peoples R China|
2.China Acad Chinese Med Sci, Inst Basic Res Clin Med, Beijing, Peoples R China
|Bao, Yan-ping,Qiu, Yi,Yan, Shi-yan,et al. Pattern of Drug Use and Depressive Symptoms among Amphetamine Type Stimulants Users in Beijing and Guangdong Province, China[J]. PLOS ONE,2013,8(4).|
|APA||Bao, Yan-ping.,Qiu, Yi.,Yan, Shi-yan.,Jia, Zhen-jun.,Li, Su-xia.,...&Liu, Zhi-min.(2013).Pattern of Drug Use and Depressive Symptoms among Amphetamine Type Stimulants Users in Beijing and Guangdong Province, China.PLOS ONE,8(4).|
|MLA||Bao, Yan-ping,et al."Pattern of Drug Use and Depressive Symptoms among Amphetamine Type Stimulants Users in Beijing and Guangdong Province, China".PLOS ONE 8.4(2013).|