北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学精神卫生研究所  > 期刊论文
学科主题: 精神卫生
题名:
Contribution of chronic diseases to disability in elderly people in countries with low and middle incomes: a 10/66 Dementia Research Group population-based survey
作者: Sousa, Renata M.1; Ferri, Cleusa P.1; Acosta, Daisy2; Albanese, Emiliano1; Guerra, Marietta3; Huang, Yueqin4; Jacob, K. S.5; Jotheeswaran, A. T.6; Llibre Rodriguez, Juan J.7; Rodriguez Pichardo, Guillermina8; Calvo Rodriguez, Marina7; Salas, Aquiles9; Luisa Sosa, Ana10; Williams, Joseph6; Zuniga, Tirso10; Prince, Martin1
刊名: LANCET
发表日期: 2009-11-01
卷: 374, 期:9704, 页:1821-1830
收录类别: SCI ; SSCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: ASSESSMENT SCHEDULE-II ; CROSS-SECTIONAL SURVEY ; PSYCHOMETRIC PROPERTIES ; WHODAS-II ; HEALTH ; EPIDEMIOLOGY ; METHODOLOGY ; PREVALENCE ; DEPENDENCY ; DEPRESSION
英文摘要:

Background Disability in elderly people in countries with low and middle incomes is little studied; according to Global Burden of Disease estimates, visual impairment is the leading contributor to years lived with disability in this population. We aimed to assess the contribution of physical, mental, and cognitive chronic diseases to disability, and the extent to which sociodemographic and health characteristics account for geographical variation in disability.

Methods We undertook cross-sectional surveys of residents aged older than 65 years (n=15 022) in 11 sites in seven countries with low and middle incomes (China, India, Cuba, Dominican Republic, Venezuela, Mexico, and Peru). Disability was assessed with the 12-item WHO disability assessment schedule 2.0. Dementia, depression, hypertension, and chronic obstructive pulmonary disease were ascertained by clinical assessment; diabetes, stroke, and heart disease by self-reported diagnosis; and sensory, gastrointestinal, skin, limb, and arthritic disorders by self-reported impairment. Independent contributions to disability scores were assessed by zero-inflated negative binomial regression and Poisson regression to generate population-attributable prevalence fractions (PAPF).

Findings In regions other than rural India and Venezuela, dementia made the largest contribution to disability (median PAPF 25.1% [IQR 19.2-43.6]). Other substantial contributors were stroke (11.4% [1.8-21.4]), limb impairment (10.5% [5.7-33.8]), arthritis (9.9% [3.2-34.8]), depression (8.3% [0.5-23.0]), eyesight problems (6.8% [1.7-17.6]), and gastrointestinal impairments (6.5% [0.3-23.1]). Associations with chronic diseases accounted for around two-thirds of prevalent disability. When zero inflation was taken into account, between-site differences in disability scores were largely attributable to compositional differences in health and sociodemographic characteristics.

Interpretation On the basis of empirical research, dementia, not blindness, is overwhelmingly the most important independent contributor to disability for elderly people in countries with low and middle incomes. Chronic diseases of the brain and mind deserve increased prioritisation. Besides disability, they lead to dependency and present stressful, complex, long-term challenges to carers. Societal costs are enormous.

语种: 英语
所属项目编号: GR066133 ; 11RG-04-1286
项目资助者: Wellcome Trust (UK) ; WHO ; US Alzheimer&prime ; s Association ; Fondo Nacional de Ciencia Y Tecnologia, Consejo de Desarrollo Cientifico Y Humanistico, Universidad Central de Venezuela (Venezuela) ; GlaxoSmithKline ; Novartis ; Lundbeck ; Pfizer ; Eisai
WOS记录号: WOS:000272370200027
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/68006
Appears in Collections:北京大学精神卫生研究所_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
2.Voluntary Hlth Serv, Dept Community Hlth, Madras, Tamil Nadu, India
3.Med Univ Havana, Fac Med Finlay Albarran, Havana, Cuba
4.Colegio Dominicano Estadist & Demografos, Santo Domingo, Dominican Rep
5.Kings Coll London, Inst Psychiat, Hlth Serv & Populat Res Dept, Ctr Publ Mental Hlth, London SE5 8AF, England
6.Univ Nacl Pedro Henriquez Urena, Dept Internal Med, Geriatr Sect, Santo Domingo, Dominican Rep
7.Natl Inst Mental Hlth Honorio Delgado Hideyo Nogu, Psychogeriatr Unit, Lima, Peru
8.Christian Med Coll & Hosp, Vellore, Tamil Nadu, India
9.Cent Univ Venezuela, Fac Med, Hop Univ Caracas, Dept Med, Caracas, Venezuela
10.Univ Nacl Autonoma Mexico, Natl Inst Neurol & Neurosurg Mexico, Mexico City 04510, DF, Mexico

Recommended Citation:
Sousa, Renata M.,Ferri, Cleusa P.,Acosta, Daisy,et al. Contribution of chronic diseases to disability in elderly people in countries with low and middle incomes: a 10/66 Dementia Research Group population-based survey[J]. LANCET,2009,374(9704):1821-1830.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Sousa, Renata M.]'s Articles
[Ferri, Cleusa P.]'s Articles
[Acosta, Daisy]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Sousa, Renata M.]‘s Articles
[Ferri, Cleusa P.]‘s Articles
[Acosta, Daisy]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace