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学科主题: 精神卫生
题名:
Abnormal anterior cingulum in patients with schizophrenia: a diffusion tensor imaging study
作者: Sun, ZG; Wang, F; Cui, LW; Breeze, J; Du, XK; Wang, XL; Cong, Z; Zhang, HY; Li, B; Hong, N; Zhang, D
关键词: anterior cingulum ; diffusion tensor imaging ; fractional anisotropy ; schizophrenia
刊名: NEUROREPORT
发表日期: 2003-10-06
DOI: 10.1097/01.wnr.0000094529.75712.48
卷: 14, 期:14, 页:1833-1836
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Neurosciences
研究领域[WOS]: Neurosciences & Neurology
关键词[WOS]: WHITE-MATTER ; BRAIN ; MRI ; PERFORMANCE ; CHILDREN ; CORTEX
英文摘要:

Diffusion tensor imaging (DTI) can non-invasively examine the molecular diffusion of water in vivo and directly reflects the anatomical integrity of neural fibers in white matter. Fractional anisotropy (FA) can be calculated from DTI data, and utilized to evaluate white matter integrity. DTI was performed on 30 patients with schizophrenia and 19 healthy controls, and their FA values were subsequently measured in multiple brain regions. Statistical analyses revealed that FA values were decreased in the anterior cingulum of schizophrenia subjects. There were no significant differences between patients and controls in any other regions. This study supports the hypothesis that schizophrenia is associated with abnormal white matter integrity of the anterior cingulum.

语种: 英语
WOS记录号: WOS:000186291100015
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/68041
Appears in Collections:北京大学精神卫生研究所_期刊论文

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作者单位: 1.Peking Univ, Inst Mental Hlth, Beijing 100083, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Dept Epidemiol & Biostat, Beijing, Peoples R China
3.McLean Hosp, Pediat Psychosis Program, Belmont, MA 02178 USA
4.Peking Univ, Peoples Hosp, Dept Radiol, Beijing 100044, Peoples R China

Recommended Citation:
Sun, ZG,Wang, F,Cui, LW,et al. Abnormal anterior cingulum in patients with schizophrenia: a diffusion tensor imaging study[J]. NEUROREPORT,2003,14(14):1833-1836.
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