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Abnormal anterior cingulum in patients with schizophrenia: a diffusion tensor imaging study
Sun, ZG; Wang, F; Cui, LW; Breeze, J; Du, XK; Wang, XL; Cong, Z; Zhang, HY; Li, B; Hong, N; Zhang, D
关键词anterior cingulum diffusion tensor imaging fractional anisotropy schizophrenia
刊名NEUROREPORT
2003-10-06
DOI10.1097/01.wnr.0000094529.75712.48
14期:14页:1833-1836
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Neurosciences
研究领域[WOS]Neurosciences & Neurology
关键词[WOS]WHITE-MATTER ; BRAIN ; MRI ; PERFORMANCE ; CHILDREN ; CORTEX
英文摘要

Diffusion tensor imaging (DTI) can non-invasively examine the molecular diffusion of water in vivo and directly reflects the anatomical integrity of neural fibers in white matter. Fractional anisotropy (FA) can be calculated from DTI data, and utilized to evaluate white matter integrity. DTI was performed on 30 patients with schizophrenia and 19 healthy controls, and their FA values were subsequently measured in multiple brain regions. Statistical analyses revealed that FA values were decreased in the anterior cingulum of schizophrenia subjects. There were no significant differences between patients and controls in any other regions. This study supports the hypothesis that schizophrenia is associated with abnormal white matter integrity of the anterior cingulum.

语种英语
WOS记录号WOS:000186291100015
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被引频次:121[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/68041
专题北京大学精神卫生研究所
作者单位1.Peking Univ, Inst Mental Hlth, Beijing 100083, Peoples R China
2.Peking Univ, Hlth Sci Ctr, Dept Epidemiol & Biostat, Beijing, Peoples R China
3.McLean Hosp, Pediat Psychosis Program, Belmont, MA 02178 USA
4.Peking Univ, Peoples Hosp, Dept Radiol, Beijing 100044, Peoples R China
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GB/T 7714
Sun, ZG,Wang, F,Cui, LW,et al. Abnormal anterior cingulum in patients with schizophrenia: a diffusion tensor imaging study[J]. NEUROREPORT,2003,14(14):1833-1836.
APA Sun, ZG.,Wang, F.,Cui, LW.,Breeze, J.,Du, XK.,...&Zhang, D.(2003).Abnormal anterior cingulum in patients with schizophrenia: a diffusion tensor imaging study.NEUROREPORT,14(14),1833-1836.
MLA Sun, ZG,et al."Abnormal anterior cingulum in patients with schizophrenia: a diffusion tensor imaging study".NEUROREPORT 14.14(2003):1833-1836.
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