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学科主题: 临床医学
题名:
Delayed renal tissue tracer transit in Tc-99m-DTPA renography correlates with postoperative renal function improvement in UPJO patients
作者: Liu, Meng1; Fu, Zhanli1; Li, Qian2; Di, Lijuan1; Zhang, Jianhua1; Fan, Yan1; Zhang, Xuchu1; Wang, Rongfu1
关键词: Anderson-Hynes pyeloplasty ; relative renal function ; response to furosemide stimulation ; tissue tracer transit ; ureteropelvic junction obstruction
刊名: NUCLEAR MEDICINE COMMUNICATIONS
发表日期: 2015-08-01
DOI: 10.1097/MNM.0000000000000332
卷: 36, 期:8, 页:833-838
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: URETEROPELVIC JUNCTION OBSTRUCTION ; UPPER URINARY-TRACT ; DIURETIC RENOGRAPHY ; DIURESIS RENOGRAPHY ; RADIONUCLIDES ; HYDRONEPHROSIS ; PYELOPLASTY ; DILATATION ; CONSENSUS ; ADULTS
英文摘要:

ObjectiveThe aim of the study was to explore the potential parameters for evaluating the improvement in relative renal function (RRF) in patients with unilateral ureteropelvic junction obstruction (UPJO) who underwent surgery. In this regard we observed the RRF expressed as the obstructed kidney′s percentage contribution to overall renal function in technetium-99m diethylenetriaminepentaacetic acid (Tc-99m-DTPA) diuretic renography.Materials and methodsData on 47 patients, who underwent Anderson-Hynes pyeloplasty for diagnosed unilateral UPJO during the period of February 2003 to October 2014, were retrospectively collected. Tc-99m-DTPA diuretic renography was performed on all patients before and after surgery, and no morphological or functional abnormalities were detected on the contralateral kidney. Several parameters, especially renal tissue tracer transit (TTT), the response to furosemide stimulation, and RRF, were evaluated. All data were analyzed with the statistical software SPSS, 17.0, and a value of P less than 0.05 was considered statistically significant.ResultsData on 42 patients were eventually retained for further analysis; five patients were excluded because of indeterminate TTT. All patients showed obstructive response to furosemide stimulation with a preoperative RRF of 4112%. Postoperative RRF of the obstructed kidneys was 47 +/- 11%, significantly higher than the preoperative RRF (P<0.05). Postoperative RRF improvement (absolute increment5%) was seen in 18/42 (43%) patients, and 24/42 (57%) of them manifested with postoperative drainage improvement. After surgery, both the RRF increment and the percentage of patients with postoperative RRF improvement in the preoperative delayed TTT group were significantly higher than those in the normal TTT group (12 +/- 7 vs. 2 +/- 4%, and 81 vs. 19%, respectively; P<0.05), but no significant difference in postoperative drainage improvement was detected between the two groups (56 vs. 54%, P>0.05). None of the other factors, including the preoperative RRF, obstructed kidney location, surgical method, sex, and age, had a significant influence on postoperative RRF improvement (P>0.05).ConclusionPreoperatively delayed TTT of Tc-99m-DTPA diuretic renography was an independent factor that correlated with RRF improvement of unilaterally hydronephrotic kidneys, and might provide valuable information for surgical decisions pertaining to UPJO patients.

语种: 英语
所属项目编号: BMU20140398
项目资助者: Seeding Grant for Medicine and Engineering Sciences of Peking University
WOS记录号: WOS:000357643600012
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/68050
Appears in Collections:北京大学第一临床医学院_核医学科_期刊论文

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作者单位: 1.Peking Univ, Dept Nucl Med, Hosp 1, Beijing 100034, Peoples R China
2.Peking Univ, Dept Ultrasound, Hosp 1, Beijing 100034, Peoples R China

Recommended Citation:
Liu, Meng,Fu, Zhanli,Li, Qian,et al. Delayed renal tissue tracer transit in Tc-99m-DTPA renography correlates with postoperative renal function improvement in UPJO patients[J]. NUCLEAR MEDICINE COMMUNICATIONS,2015,36(8):833-838.
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