IR@PKUHSC  > 北京大学第一临床医学院
学科主题临床医学
Early Systolic Blood Pressure Changes in Incident Hemodialysis Patients Are Associated with Mortality in the First Year
Sipahioglu, Murat H.1,2; Usvyat, Len2; Liu, Li2,4; Abbas, Samer R.2; Raimann, Jochen G.2; Rosales, Laura2; Levin, Nathan W.2; Kotanko, Peter2,3
关键词Hemodialysis Mortality Systolic blood pressure
刊名KIDNEY & BLOOD PRESSURE RESEARCH
2012
DOI10.1159/000342634
35期:6页:663-670
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Physiology ; Urology & Nephrology ; Peripheral Vascular Disease
研究领域[WOS]Physiology ; Urology & Nephrology ; Cardiovascular System & Cardiology
关键词[WOS]CHRONIC KIDNEY-DISEASE ; UNITED-STATES ; SURVIVAL ; DIALYSIS ; OUTCOMES ; RISK ; RACE
英文摘要

Background: In incident hemodialysis (HD) patients, the relationship between early systolic blood pressure (SBP) dynamics and mortality is unknown. Methods: Baseline SBP levels were stratified into 5 categories ranging from <120 and >= 180 mm Hg. Early pre-HD SBP change was defined as the slope of pre-HD SBP from week 1 to 12 and categorized in quartiles (Q1, lowest slope). SBP slopes were computed for each patient by simple linear regression. Results: In 3,446 incident HD patients (42% females, 44% black, age 62 +/- 15 years), the median pre-HD SBP slope was -1.7 (Q1) to +2.3 (Q4) mm Hg/week. In an adjusted multivariate Cox regression analysis, patients with declining SBP (slope Q1) had higher mortality compared to patients with increasing pre-HD SBP (slope Q4) at 12 months (hazard ratio 2.01, 95% confidence interval 1.35-3.01). In addition, patients with baseline pre-HD SBP <120 mm Hg showed higher mortality compared to the reference group (SBP >= 180 mm Hg) at 12 months (hazard ratio 1.89, 95% confidence interval 1.03-3.45). Conclusion: Baseline pre-HD SBP and early SBP dynamics are associated with mortality in the first year of dialysis. Patients who had low (pre-HD SBP <120 mm Hg) or declining SBP had the highest mortality rates. Particular attention is warranted in incident HD patients with low or declining SBP. Copyright (C) 2012 S. Karger AG, Basel

语种英语
WOS记录号WOS:000314461100035
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/68075
专题北京大学第一临床医学院
作者单位1.Renal Res Inst, New York, NY 10128 USA
2.Beth Israel Deaconess Med Ctr, New York, NY 10003 USA
3.Erciyes Univ, Dept Nephrol, Fac Med, Kayseri, Turkey
4.Peking Univ, Hosp 1, Inst & Div Nephrol, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Sipahioglu, Murat H.,Usvyat, Len,Liu, Li,et al. Early Systolic Blood Pressure Changes in Incident Hemodialysis Patients Are Associated with Mortality in the First Year[J]. KIDNEY &amp; BLOOD PRESSURE RESEARCH,2012,35(6):663-670.
APA Sipahioglu, Murat H..,Usvyat, Len.,Liu, Li.,Abbas, Samer R..,Raimann, Jochen G..,...&Kotanko, Peter.(2012).Early Systolic Blood Pressure Changes in Incident Hemodialysis Patients Are Associated with Mortality in the First Year.KIDNEY & BLOOD PRESSURE RESEARCH,35(6),663-670.
MLA Sipahioglu, Murat H.,et al."Early Systolic Blood Pressure Changes in Incident Hemodialysis Patients Are Associated with Mortality in the First Year".KIDNEY & BLOOD PRESSURE RESEARCH 35.6(2012):663-670.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Sipahioglu, Murat H.]的文章
[Usvyat, Len]的文章
[Liu, Li]的文章
百度学术
百度学术中相似的文章
[Sipahioglu, Murat H.]的文章
[Usvyat, Len]的文章
[Liu, Li]的文章
必应学术
必应学术中相似的文章
[Sipahioglu, Murat H.]的文章
[Usvyat, Len]的文章
[Liu, Li]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。