IR@PKUHSC  > 北京大学口腔医学院  > 口腔修复科
学科主题口腔医学
Pharmacokinetics of CNT-based Drug Delivery Systems
Ye, Rui1,2; Wang, Sheng1,2; Wang, Jing3; Luo, Zhiqiang4; Peng, Qiang1; Cai, Xiaoxiao1; Lin, Yunfeng1
关键词Absorption CNT distribution drug release excretion intracellular internalization metabolism tumor targeting
刊名CURRENT DRUG METABOLISM
2013-10-01
14期:8页:910-920
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Pharmacology & Pharmacy
资助者National Natural Science Foundation of China ; Foundation for the Author of National Excellent Doctoral Dissertation of China ; Funding for Distinguished Young Scientists in Sichuan ; Ministry of Education of China ; National Natural Science Foundation of China ; Foundation for the Author of National Excellent Doctoral Dissertation of China ; Funding for Distinguished Young Scientists in Sichuan ; Ministry of Education of China
研究领域[WOS]Biochemistry & Molecular Biology ; Pharmacology & Pharmacy
关键词[WOS]WALLED CARBON NANOTUBES ; RECEPTOR-MEDIATED ENDOCYTOSIS ; NEAR-INFRARED FLUORESCENCE ; SINGLE-PARTICLE TRACKING ; IN-VIVO ; CANCER-CELLS ; RAMAN-SPECTROSCOPY ; CONTROLLED-RELEASE ; LIVING CELLS ; MACROMOLECULAR THERAPEUTICS
英文摘要

Carbon nanotubes (CNT) are allotropes of carbon with a cylindrical nanostructure. They have recently aroused great interests as drug carriers, but their pharmacokinetic profiles which determine their potentials in clinical application are yet to be fully understood. Therefore, this overview attempts to outline the processes of absorption, distribution, metabolism and excretion (ADME) that govern the pharmacokinetics of CNT. In addition, the molecular mechanisms of intracellular internalization and drug release are also discussed.

语种英语
所属项目编号81071273 ; 31170929 ; 81201211 ; FANEDD 200977 ; 2010JQ0066 ; 20110181120071
资助者National Natural Science Foundation of China ; Foundation for the Author of National Excellent Doctoral Dissertation of China ; Funding for Distinguished Young Scientists in Sichuan ; Ministry of Education of China ; National Natural Science Foundation of China ; Foundation for the Author of National Excellent Doctoral Dissertation of China ; Funding for Distinguished Young Scientists in Sichuan ; Ministry of Education of China
WOS记录号WOS:000326168900012
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/68104
Collection北京大学口腔医学院_口腔修复科
作者单位1.Sichuan Univ, State Key Lab Oral Dis, Chengdu 610041, Peoples R China
2.Sichuan Univ, West China Sch Stomatol, Dept Orthodont, Chengdu 610041, Peoples R China
3.Tongji Univ, Shanghai Peoples Hosp 10, Sch Med, Dept Stomatol, Shanghai 200092, Peoples R China
4.Peking Univ, Sch Stomatol, Dept Prosthodont, Beijing 100871, Peoples R China
Recommended Citation
GB/T 7714
Ye, Rui,Wang, Sheng,Wang, Jing,et al. Pharmacokinetics of CNT-based Drug Delivery Systems[J]. CURRENT DRUG METABOLISM,2013,14(8):910-920.
APA Ye, Rui.,Wang, Sheng.,Wang, Jing.,Luo, Zhiqiang.,Peng, Qiang.,...&Lin, Yunfeng.(2013).Pharmacokinetics of CNT-based Drug Delivery Systems.CURRENT DRUG METABOLISM,14(8),910-920.
MLA Ye, Rui,et al."Pharmacokinetics of CNT-based Drug Delivery Systems".CURRENT DRUG METABOLISM 14.8(2013):910-920.
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