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Trapping volumetric measurement by multidetector CT in chronic obstructive pulmonary disease: Effect of CT threshold
Wang, Xiaohua1; Duan, Jianghui2; Du, Yipeng3; Shen, Ning3; He, Bei3; Yuan, Huishu1
关键词X-ray computed tomography volume measurement chronic obstructive pulmonary disease
刊名MEDICAL PHYSICS
2013-08-01
DOI10.1118/1.4813906
40期:8
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]QUANTITATIVE COMPUTED-TOMOGRAPHY ; REDUCTION SURGERY ; MICROSCOPIC MORPHOMETRY ; DOSE CT ; EMPHYSEMA ; QUANTIFICATION ; EXPIRATION ; DENSITY ; COPD
英文摘要

Purpose: The purpose of this study was to evaluate the effect of various computed tomography (CT) thresholds on trapping volumetric measurements by multidetector CT in chronic obstructive pulmonary disease (COPD).

Methods: Twenty-three COPD patients were scanned with a 64-slice CT scanner in both the inspiratory and expiratory phase. CT thresholds of -950 Hu in inspiration and -950 to -890 Hu in expiration were used, after which trapping volumetric measurements were made using computer software. Trapping volume percentage (Vtrap%) under the different CT thresholds in the expiratory phase and below -950 Hu in the inspiratory phase was compared and correlated with lung function.

Results: Mean Vtrap% was similar under -930 Hu in the expiratory phase and below -950 Hu in the inspiratory phase, being 13.18 +/- 9.66 and 13.95 +/- 6.72 (both lungs), respectively; this difference was not significant (P = 0.240). Vtrap% under -950 Hu in the inspiratory phase and below the -950 to -890 Hu threshold in the expiratory phase was moderately negatively correlated with the ratio of forced expiratory volume in one second to forced vital capacity and the measured value of forced expiratory volume in one second as a percentage of the predicted value.

Conclusions: Trapping volumetric measurement with multidetector CT is a promising method for the quantification of COPD. It is important to know the effect of various CT thresholds on trapping volumetric measurements. (C) 2013 American Association of Physicists in Medicine.

语种英语
WOS记录号WOS:000322735900048
项目编号BMU20110176
资助机构Beijing University
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/68136
专题北京大学第三临床医学院_呼吸科
北京大学第三临床医学院_放射科
作者单位1.Peking Univ, Dept Radiol, Hosp 3, Beijing 100191, Peoples R China
2.Peking Univ, Sch Med, Beijing 100191, Peoples R China
3.Peking Univ, Hosp 3, Dept Resp Internal Med, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Wang, Xiaohua,Duan, Jianghui,Du, Yipeng,et al. Trapping volumetric measurement by multidetector CT in chronic obstructive pulmonary disease: Effect of CT threshold[J]. MEDICAL PHYSICS,2013,40(8).
APA Wang, Xiaohua,Duan, Jianghui,Du, Yipeng,Shen, Ning,He, Bei,&Yuan, Huishu.(2013).Trapping volumetric measurement by multidetector CT in chronic obstructive pulmonary disease: Effect of CT threshold.MEDICAL PHYSICS,40(8).
MLA Wang, Xiaohua,et al."Trapping volumetric measurement by multidetector CT in chronic obstructive pulmonary disease: Effect of CT threshold".MEDICAL PHYSICS 40.8(2013).
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