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学科主题: 临床医学
题名:
Trapping volumetric measurement by multidetector CT in chronic obstructive pulmonary disease: Effect of CT threshold
作者: Wang, Xiaohua1; Duan, Jianghui2; Du, Yipeng3; Shen, Ning3; He, Bei3; Yuan, Huishu1
关键词: X-ray computed tomography ; volume measurement ; chronic obstructive pulmonary disease
刊名: MEDICAL PHYSICS
发表日期: 2013-08-01
DOI: 10.1118/1.4813906
卷: 40, 期:8
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: QUANTITATIVE COMPUTED-TOMOGRAPHY ; REDUCTION SURGERY ; MICROSCOPIC MORPHOMETRY ; DOSE CT ; EMPHYSEMA ; QUANTIFICATION ; EXPIRATION ; DENSITY ; COPD
英文摘要:

Purpose: The purpose of this study was to evaluate the effect of various computed tomography (CT) thresholds on trapping volumetric measurements by multidetector CT in chronic obstructive pulmonary disease (COPD).

Methods: Twenty-three COPD patients were scanned with a 64-slice CT scanner in both the inspiratory and expiratory phase. CT thresholds of -950 Hu in inspiration and -950 to -890 Hu in expiration were used, after which trapping volumetric measurements were made using computer software. Trapping volume percentage (Vtrap%) under the different CT thresholds in the expiratory phase and below -950 Hu in the inspiratory phase was compared and correlated with lung function.

Results: Mean Vtrap% was similar under -930 Hu in the expiratory phase and below -950 Hu in the inspiratory phase, being 13.18 +/- 9.66 and 13.95 +/- 6.72 (both lungs), respectively; this difference was not significant (P = 0.240). Vtrap% under -950 Hu in the inspiratory phase and below the -950 to -890 Hu threshold in the expiratory phase was moderately negatively correlated with the ratio of forced expiratory volume in one second to forced vital capacity and the measured value of forced expiratory volume in one second as a percentage of the predicted value.

Conclusions: Trapping volumetric measurement with multidetector CT is a promising method for the quantification of COPD. It is important to know the effect of various CT thresholds on trapping volumetric measurements. (C) 2013 American Association of Physicists in Medicine.

语种: 英语
所属项目编号: BMU20110176
项目资助者: Beijing University
WOS记录号: WOS:000322735900048
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/68136
Appears in Collections:北京大学第三临床医学院_放射科_期刊论文

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作者单位: 1.Peking Univ, Dept Radiol, Hosp 3, Beijing 100191, Peoples R China
2.Peking Univ, Sch Med, Beijing 100191, Peoples R China
3.Peking Univ, Hosp 3, Dept Resp Internal Med, Beijing 100191, Peoples R China

Recommended Citation:
Wang, Xiaohua,Duan, Jianghui,Du, Yipeng,et al. Trapping volumetric measurement by multidetector CT in chronic obstructive pulmonary disease: Effect of CT threshold[J]. MEDICAL PHYSICS,2013,40(8).
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