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学科主题: 临床医学
题名:
Surface Noninvasive Detection of Breast Tumors Using Fourier Transform Infrared Spectroscopy
作者: Shen Wei1; Zhao Hong-Mei1; Lei Yu-Tao1; Ling Xiao-Feng1; Zhu Qing2; Zhang Ying2; Zhang Yuan-Fu2; Xu Yi-Zhuang2; Wu Jin-Guang2; Wu Yang-Feng3; Li Hui-Juan3; Xu Zhi1
关键词: Fourier transform infrared (FTIR) spectroscopy ; Attenuated total reflectance (ATR) ; Optical fiber ; Breast cancer
刊名: CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
发表日期: 2012-11-10
DOI: 10.7503/cjcu20120410
卷: 33, 期:11, 页:2390-2396
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
关键词[WOS]: BASAL-CELL CARCINOMA ; IN-VIVO ; FTIR SPECTROSCOPY ; NUCLEIC-ACID ; CANCER ; SKIN ; TISSUES ; DIAGNOSIS ; SPECTRA ; SITU
英文摘要:

To identify Fourier transform infrared (FTIR) spectra of normal and abnormal (mass) breast skin at molecular level, infrared scanning was performed for 46 healthy volunteers and 113 inpatients with palpable breast masses. Breast surface were measured by FTIR spectrometer equipped with attenuated total reflectance (ATR) probe and infrared optical fiber. The results showed that the spectra of healthy volunteers tended to be consistent; the FTIR spectra of control, benign and malignant groups differed owing to content or configuration alterations of nucleic acids, proteins, lipids and carbohydrates, and changes in differential diagnosis of benign and malignant were predominantly observed in the 1080 cm(-1) peak absorbance, commonly associated with nucleic acids.

语种: 中文
WOS记录号: WOS:000311593700006
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/68147
Appears in Collections:北京大学第三临床医学院_普通外科_期刊论文

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作者单位: 1.Peking Univ, Clin Res Inst, Beijing 100191, Peoples R China
2.Peking Univ, Hosp 3, Dept Gen Surg, Beijing 100191, Peoples R China
3.Peking Univ, Coll Chem & Mol Engn, Beijing 100871, Peoples R China

Recommended Citation:
Shen Wei,Zhao Hong-Mei,Lei Yu-Tao,et al. Surface Noninvasive Detection of Breast Tumors Using Fourier Transform Infrared Spectroscopy[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2012,33(11):2390-2396.
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