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学科主题: 药学
题名:
Effects of collagen types II and X on the kinetics of crystallization of calcium phosphate in biomineralization
作者: Guo, Y; Huang, J; Xu, SJ; Wang, K
关键词: type II collagen ; type X collagen ; biomineralization ; kinetics
刊名: PROGRESS IN NATURAL SCIENCE
发表日期: 2002
卷: 12, 期:1, 页:17-19
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Materials Science, Multidisciplinary ; Multidisciplinary Sciences
研究领域[WOS]: Materials Science ; Science & Technology - Other Topics
关键词[WOS]: MINERALIZATION
英文摘要:

The effects of the components of cartilages matrix on the process of endochondral ossification and the kinetics of crystal growth of calcium phosphate have been studied in the presence of type II or X collagen. During the experiments, type I collagen was added as the seed material. FT-IR analysis shows that calcium phosphate crystallized on the surface of type I collagen was mainly hydroxyapatite. Both type II and X collagens could reduce the growth rate of calcium phosphate crystals, and the effect of type X collagen is more obvious. The reaction was in the fourth order in the presence of type II collagen. The results showed that type II or X collagen had the ability to make Ca2+ accumulate in the process of endochondral ossification, but has little effect on crystal growth and the product of biomineralization.

语种: 英语
WOS记录号: WOS:000172948200003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/68153
Appears in Collections:北京大学药学院_化学生物学系_期刊论文

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作者单位: Peking Univ, Sch Pharmaceut Sci, Dept Biol Chem, Beijing 100083, Peoples R China

Recommended Citation:
Guo, Y,Huang, J,Xu, SJ,et al. Effects of collagen types II and X on the kinetics of crystallization of calcium phosphate in biomineralization[J]. PROGRESS IN NATURAL SCIENCE,2002,12(1):17-19.
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