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学科主题: 公共卫生
题名:
Physical Features Observation: Is it Repeatable in Zygosity Determination of Chinese Adult Twins?
作者: Gao, Wenjing; Li, Liming; Cao, Weihua; Zhan, Siyan; Zhao, Yunlong; Wang, Hui; Hu, Yonghua
关键词: twins ; zygosity ; validation study
刊名: TWIN RESEARCH AND HUMAN GENETICS
发表日期: 2010-02-01
卷: 13, 期:1, 页:96-100
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Genetics & Heredity ; Obstetrics & Gynecology
研究领域[WOS]: Genetics & Heredity ; Obstetrics & Gynecology
关键词[WOS]: QUESTIONNAIRE
英文摘要:

This study reports on the inter- and intrarater reliability of physical features observation. Study subjects were 176 Chinese adult persons, consisting of 89 males and 87 females. Three trained research assistants responded simultaneously and respectively to 12 items regarding the subject′s physical features including ′hair′, ′Mongoloid folds′, left and right ′ear lobes′, ′earwax′, ′nostril shape′, ′tongue rolling′, left and right ′hitchhiker′s thumb′, ′mid-digital hair′ and left and right ′simian crease′ at the moment of interview. And 14 days later, these subjects received the same observation once again. The results showed that the inter- and intra-observer agreements of ′hair′, ′earwax′, ′tongue rolling′, ′mid-digital hair′ and ′simian crease′ were almost perfect with most kappa (kappa) coefficients >= .80, while ′Mongoloid fold′ and ′nostril shape′ showed poor inter-observer agreement and ′nostril shape′ showed poor intra-observer agreement (kappa < .40). Two other physical features, ′hitchhiker′s thumb′ and ′ear lobes′ showed moderate inter-observer agreement and three features, ′hitchhiker′s thumb′, ′ear lobes′ and ′Mongoloid fold′, showed moderate intra-observer agreement (.40 <= kappa <.80). In conclusion, this study suggests that as far as reliability is concerned, the five features which were ′hair′, ′earwax′, ′tongue rolling′, ′mid-digital hair′ and ′simian crease′ could be considered in zygosity determination of Chinese adult twins, while the two features, ′Mongoloid fold′ and ′nostril shape′, should be abandoned.

语种: 英语
所属项目编号: 01-746 ; 20062007
项目资助者: China Medical Board ; Youth Fund of the School of Public Health, Peking University
WOS记录号: WOS:000275258400010
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/68160
Appears in Collections:北京大学公共卫生学院_期刊论文

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作者单位: Peking Univ, Hlth Sci Ctr, Sch Publ Hlth, Dept Epidemiol & Biostat, Beijing 100191, Peoples R China

Recommended Citation:
Gao, Wenjing,Li, Liming,Cao, Weihua,et al. Physical Features Observation: Is it Repeatable in Zygosity Determination of Chinese Adult Twins?[J]. TWIN RESEARCH AND HUMAN GENETICS,2010,13(1):96-100.
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