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Physical Features Observation: Is it Repeatable in Zygosity Determination of Chinese Adult Twins?
Gao, Wenjing; Li, Liming; Cao, Weihua; Zhan, Siyan; Zhao, Yunlong; Wang, Hui; Hu, Yonghua
关键词twins zygosity validation study
刊名TWIN RESEARCH AND HUMAN GENETICS
2010-02-01
13期:1页:96-100
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Genetics & Heredity ; Obstetrics & Gynecology
研究领域[WOS]Genetics & Heredity ; Obstetrics & Gynecology
关键词[WOS]QUESTIONNAIRE
英文摘要

This study reports on the inter- and intrarater reliability of physical features observation. Study subjects were 176 Chinese adult persons, consisting of 89 males and 87 females. Three trained research assistants responded simultaneously and respectively to 12 items regarding the subject′s physical features including ′hair′, ′Mongoloid folds′, left and right ′ear lobes′, ′earwax′, ′nostril shape′, ′tongue rolling′, left and right ′hitchhiker′s thumb′, ′mid-digital hair′ and left and right ′simian crease′ at the moment of interview. And 14 days later, these subjects received the same observation once again. The results showed that the inter- and intra-observer agreements of ′hair′, ′earwax′, ′tongue rolling′, ′mid-digital hair′ and ′simian crease′ were almost perfect with most kappa (kappa) coefficients >= .80, while ′Mongoloid fold′ and ′nostril shape′ showed poor inter-observer agreement and ′nostril shape′ showed poor intra-observer agreement (kappa < .40). Two other physical features, ′hitchhiker′s thumb′ and ′ear lobes′ showed moderate inter-observer agreement and three features, ′hitchhiker′s thumb′, ′ear lobes′ and ′Mongoloid fold′, showed moderate intra-observer agreement (.40 <= kappa <.80). In conclusion, this study suggests that as far as reliability is concerned, the five features which were ′hair′, ′earwax′, ′tongue rolling′, ′mid-digital hair′ and ′simian crease′ could be considered in zygosity determination of Chinese adult twins, while the two features, ′Mongoloid fold′ and ′nostril shape′, should be abandoned.

语种英语
WOS记录号WOS:000275258400010
项目编号01-746 ; 20062007
资助机构China Medical Board ; Youth Fund of the School of Public Health, Peking University
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/68160
专题北京大学公共卫生学院
北京大学公共卫生学院_公共卫生学院
北京大学临床肿瘤学院_麻醉科
作者单位Peking Univ, Hlth Sci Ctr, Sch Publ Hlth, Dept Epidemiol & Biostat, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Gao, Wenjing,Li, Liming,Cao, Weihua,et al. Physical Features Observation: Is it Repeatable in Zygosity Determination of Chinese Adult Twins?[J]. TWIN RESEARCH AND HUMAN GENETICS,2010,13(1):96-100.
APA Gao, Wenjing.,Li, Liming.,Cao, Weihua.,Zhan, Siyan.,Zhao, Yunlong.,...&Hu, Yonghua.(2010).Physical Features Observation: Is it Repeatable in Zygosity Determination of Chinese Adult Twins?.TWIN RESEARCH AND HUMAN GENETICS,13(1),96-100.
MLA Gao, Wenjing,et al."Physical Features Observation: Is it Repeatable in Zygosity Determination of Chinese Adult Twins?".TWIN RESEARCH AND HUMAN GENETICS 13.1(2010):96-100.
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