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学科主题: 公共卫生
题名:
Use of drug treatment for secondary prevention of cardiovascular disease in urban and rural communities of China: China Kadoorie Biobank Study of 0.5 million people
作者: Chen, Yiping1,2; Li, Liming3,4; Zhang, Qiuli1,2; Clarke, Robert1,2; Chen, Junshi5; Guo, Yu3; Bian, Zheng3; Pan, Xianhai6; Peto, Richard1,2; Tao, Ran7; Shi, Kunxiang8; Collins, Rory1,2; Ma, Liangcai9; Sun, Huarong10; Chen, Zhengming1,2; China Kadoorie Biobank Study
关键词: Ischemic heart disease ; Stroke ; Secondary prevention ; Cardiovascular medication ; Rural and urban communities ; China
刊名: INTERNATIONAL JOURNAL OF CARDIOLOGY
发表日期: 2014-03-01
DOI: 10.1016/j.ijcard.2013.12.065
卷: 172, 期:1, 页:88-95
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Cardiac & Cardiovascular Systems
研究领域[WOS]: Cardiovascular System & Cardiology
关键词[WOS]: HIGH-RISK PATIENTS ; MYOCARDIAL-INFARCTION ; RANDOMIZED-TRIALS ; HEART-FAILURE ; HEALTH-CARE ; SELF-REPORT ; MORTALITY ; VALIDITY ; EVENTS ; STROKE
英文摘要:

Aims: Relatively little is known about the use of medication for the secondary prevention of cardiovascular disease (CVD) events in China, and the relevance to it of socioeconomic, lifestyle and health-related factors.

Methods and results: We analysed cross-sectional data from the China Kadoorie Biobank (CKB) of 512,891 adults aged 30-79 years recruited from 1737 rural and urban communities in China. Information about doctor-diagnosed ischaemic heart disease (IHD) and stroke, and the use of medication for the secondary prevention of CVD events, were recorded by interview. Multivariate logistic regression was used to estimate odds ratios (ORs) for use of secondary preventive treatment, adjusting simultaneously for age, sex, area and education. Overall, 23,129 (4.5%) participants reported a history of CVD (3.0% IHD, 1.7% stroke). Among them, 35% reported current use of any of 6 classes of drug (anti-platelet, statins, diuretics, ACE-I, beta-blockers or calcium-channel blockers) for the prevention of CVD events, with the rate of usage greater in those with older age, higher levels of income, education, BMI or blood pressure. The use of these agents was associated positively with history of diagnosed hypertension (OR 7.5; 95% confidence intervals: 7.08-8.06) and diabetes (1.40; 1.28-1.52) and inversely with self-rated health status, but there was no association with years since diagnosis.

Conclusions: Despite recent improvements in hospital care in China, only one in three individuals with prior CVD was routinely treated with any proven secondary preventive drugs. The treatment rates were correlated with the existence of other risk factors, in particular evidence of hypertension. (C) 2013 The Authors. Published by Elsevier Ireland Ltd. All rights reserved.

语种: 英语
所属项目编号: 088158/Z/09/Z ; 2011BAI09B01
项目资助者: Kadoorie Charitable Foundation in Hong Kong ; Wellcome Trust in the UK ; National Key Technology Research and Development Program in the 12th Five-Year Plan, Ministry of Science and Technology, People&prime ; s Republic of China ; Clinical Trial Service Unit ; Epidemiological Studies Unit (CTSU) at Oxford University ; UK Medical Research Council ; British Heart Foundation ; Cancer Research UK
WOS记录号: WOS:000331721600117
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/68170
Appears in Collections:北京大学公共卫生学院_期刊论文

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作者单位: 1.Hainan CDC, Haikou, Hainan, Peoples R China
2.China Natl Ctr Food Safety Risk Assessment, Beijing, Peoples R China
3.Univ Oxford, Nuffield Dept Populat Hlth, Clin Trial Serv Unit, Oxford OX3 7LF, England
4.Univ Oxford, Nuffield Dept Populat Hlth, Epidemiol Studies Unit CTSU, Oxford OX3 7LF, England
5.Peking Univ, Hlth Sci Ctr, Sch Publ Hlth, Dept Epidemiol & Biostat, Beijing 100871, Peoples R China
6.Chinese Acad Med Sci, Beijing 100730, Peoples R China
7.Jiangsu CDC, NCDs Prevent & Control Dept, Nanjing, Jiangsu, Peoples R China
8.Tongxiang CDC, Tongxiang, Zhejiang, Peoples R China
9.Suzhou CDC, NCDs Prevent & Control Dept, Suzhou, Jiangsu, Peoples R China
10.Huixian CDC, NCDs Prevent & Control Dept, Huixian, Henan, Peoples R China

Recommended Citation:
Chen, Yiping,Li, Liming,Zhang, Qiuli,et al. Use of drug treatment for secondary prevention of cardiovascular disease in urban and rural communities of China: China Kadoorie Biobank Study of 0.5 million people[J]. INTERNATIONAL JOURNAL OF CARDIOLOGY,2014,172(1):88-95.
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