IR@PKUHSC  > 北京大学临床肿瘤学院  > 超声科
学科主题临床医学
Evaluation of primary malignancies of the liver using contrast-enhanced sonography: Correlation with pathology
Fan, ZH; Chen, MH; Dai, Y; Wang, YB; Yan, K; Wu, W; Yang, W; Yin, SS
关键词contrast agents primary malignancies of the liver sonography
刊名AMERICAN JOURNAL OF ROENTGENOLOGY
2006-06-01
DOI10.2214/AJR.05.0943
186期:6页:1512-1519
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]SMALL HEPATOCELLULAR-CARCINOMA ; PERIPHERAL CHOLANGIOCARCINOMA ; CIRRHOTIC LIVERS ; KUPFFER CELLS ; LESIONS ; CT ; DIFFERENTIATION ; AGENT
英文摘要

OBJECTIVE. Our purpose was to investigate the correlation of contrast-enhanced sonographic patterns with the histopathology of primary malignancies of the liver.

MATERIAL AND METHODS. Of the 318 contrast-enhanced sonographic examinations performed between April and September 2004, 95 patients with 117 lesions confirmed by surgery or biopsy pathology were reviewed in this study. We analyzed the enhancement time and patterns according to the types and degrees of pathologic differentiation.

RESULTS. All 65 moderately to poorly differentiated hepatocellular carcinomas (HCCs) enhanced in the arterial phase, and 96.9% (63 lesions) of them quickly washed out in the portal venous phase. All 32 well-differentiated HCCs enhanced in the arterial phase, and 50.0% (16 lesions) washed out slowly during the late phase. The washout time of the two differentiated types was significantly different (p < 0.05). Seventy-five percent of the clear cell carcinomas (12/16) enhanced in the arterial phase, 25% (4/16) did not enhance until the portal venous phase, and 31.3% (5/16) of the clear cell carcinomas washed out slowly during the late phase. The enhancement and washout times of clear cell carcinomas were significantly different than those of moderately to poorly differentiated HCCs (p < 0.05). All four intrahepatic cholangiocarcinomas presented the same patterns as moderately to poorly differentiated HCCs: enhanced in the arterial phase and quickly washed out in the portal venous phase. Among the 72 lesions enhanced homogeneously, 46 lesions (63.9%) were smaller than 3 cm. Thirty-seven lesions (82.2%) of the 45 lesions that enhanced heterogeneously were larger than 3 cm (including the four cholangiocarcinomas). Larger lesions were mainly less differentiated. There were significant differences in tumor sizes in regard to cellular differentiations and types.

CONCLUSION. Our study showed that the enhancement manifestations of primary malignancies of the liver are related to pathologic types and grades. Contrast-enhanced sonograms may provide the histopathologic information for malignant tumors of the liver.

语种英语
WOS记录号WOS:000237759300007
引用统计
被引频次:47[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/68188
专题北京大学临床肿瘤学院_超声科
作者单位Peking Univ, Sch Oncol, Dept Ultrasound, Beijing 100036, Peoples R China
推荐引用方式
GB/T 7714
Fan, ZH,Chen, MH,Dai, Y,et al. Evaluation of primary malignancies of the liver using contrast-enhanced sonography: Correlation with pathology[J]. AMERICAN JOURNAL OF ROENTGENOLOGY,2006,186(6):1512-1519.
APA Fan, ZH.,Chen, MH.,Dai, Y.,Wang, YB.,Yan, K.,...&Yin, SS.(2006).Evaluation of primary malignancies of the liver using contrast-enhanced sonography: Correlation with pathology.AMERICAN JOURNAL OF ROENTGENOLOGY,186(6),1512-1519.
MLA Fan, ZH,et al."Evaluation of primary malignancies of the liver using contrast-enhanced sonography: Correlation with pathology".AMERICAN JOURNAL OF ROENTGENOLOGY 186.6(2006):1512-1519.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Fan, ZH]的文章
[Chen, MH]的文章
[Dai, Y]的文章
百度学术
百度学术中相似的文章
[Fan, ZH]的文章
[Chen, MH]的文章
[Dai, Y]的文章
必应学术
必应学术中相似的文章
[Fan, ZH]的文章
[Chen, MH]的文章
[Dai, Y]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。