IR@PKUHSC  > 北京大学药学院
学科主题药学
New coumarin glycosides from the leaves of Diospyros crassiflora (Hiern)
Akak, Carine Mvot1,2; Djama, Celine Mbazoa2; Nkengfack, Augustin Ephrem2; Tu, Peng-Fei1; Lei, Lian-Di1
关键词Diospyros crassiflora Ebenaceae Coumarin glycosides Diosfeboside A Diosfeboside B Cytotoxic activity
刊名FITOTERAPIA
2010-10-01
DOI10.1016/j.fitote.2010.05.011
81期:7页:873-877
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Medicinal ; Pharmacology & Pharmacy
资助者Ministry of Higher Education of Cameroon (MINESUP) ; China Scholarship Council (CSC) ; Ministry of Higher Education of Cameroon (MINESUP) ; China Scholarship Council (CSC)
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]4-HYDROXYCOUMARIN ; NAPHTHOQUINONE ; BIOSYNTHESIS ; DERIVATIVES ; DICOUMAROL ; INHIBITORS ; BETALAINS ; INTEGRASE ; DEFENSE
英文摘要

Two new 5-methylcoumarin glycosides named diosfeboside A (1) and B (2) and five known compounds namely kaempferol 3-O-alpha-L-rhamnopyranosyl-(1 -> 2)-beta-D-glucopyranoside (3), ursolic acid (4), betulinic acid (5), stigmasterol (6) and stigmasterol 3-O-beta-D-glucopyranoside (7) were isolated from the leaves of Diospyros crassiflora (Hiern). Their structures were established through interpretation of 1 and 2D NMR, mass spectra analysis and comparison with reported data. In vitro cytotoxic activity of the new compounds against human carcinoma cell lines (HL-60, Bel-7402, BGC-823, and KB) was evaluated and no cytotoxicity was observed for each of them. (C) 2010 Elsevier B.V. All rights reserved.

语种英语
资助者Ministry of Higher Education of Cameroon (MINESUP) ; China Scholarship Council (CSC) ; Ministry of Higher Education of Cameroon (MINESUP) ; China Scholarship Council (CSC)
WOS记录号WOS:000282864800035
Citation statistics
Cited Times:11[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/68200
Collection北京大学药学院
作者单位1.Peking Univ Hlth Sci Ctr, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
2.Univ Yaounde 1, Fac Sci, Dept Organ Chem, Yaounde, Cameroon
Recommended Citation
GB/T 7714
Akak, Carine Mvot,Djama, Celine Mbazoa,Nkengfack, Augustin Ephrem,et al. New coumarin glycosides from the leaves of Diospyros crassiflora (Hiern)[J]. FITOTERAPIA,2010,81(7):873-877.
APA Akak, Carine Mvot,Djama, Celine Mbazoa,Nkengfack, Augustin Ephrem,Tu, Peng-Fei,&Lei, Lian-Di.(2010).New coumarin glycosides from the leaves of Diospyros crassiflora (Hiern).FITOTERAPIA,81(7),873-877.
MLA Akak, Carine Mvot,et al."New coumarin glycosides from the leaves of Diospyros crassiflora (Hiern)".FITOTERAPIA 81.7(2010):873-877.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
谷歌学术
谷歌学术Similar articles in
[Akak, Carine Mvot]'s Articles
[Djama, Celine Mbazoa]'s Articles
[Nkengfack, Augustin Ephrem]'s Articles
百度学术
百度学术Similar articles in
[Akak, Carine Mvot]'s Articles
[Djama, Celine Mbazoa]'s Articles
[Nkengfack, Augustin Ephrem]'s Articles
必应学术
必应学术Similar articles in
[Akak, Carine Mvot]'s Articles
[Djama, Celine Mbazoa]'s Articles
[Nkengfack, Augustin Ephrem]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.