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学科主题临床医学
Comparison of clinical outcomes for patients with clinical N0 and pathologic N2 non-small cell lung cancer after thoracoscopic lobectomy and open lobectomy: A retrospective analysis of 76 patients
Li, Yun; Wang, Jung
关键词video-assisted thoracoscopic surgery thoracotomy non-small cell lung cancer major pulmonary resection mediastinal lymph node
刊名JOURNAL OF SURGICAL ONCOLOGY
2012-09-01
DOI10.1002/jso.23104
106期:4页:431-435
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Oncology ; Surgery
研究领域[WOS]Oncology ; Surgery
关键词[WOS]ASSISTED THORACIC-SURGERY ; COMPLETE RESECTION ; DISSECTION ; SURVIVAL ; DISEASE
英文摘要

Objective To compare outcomes between thoracoscopic and thoracotomy lobectomy for patients with cN0-pN2 NSCLC. Methods One hundred eighty-two cN0 patients (including 29 pN2) underwent VATS lobectomy between September 2006 and December 2009, and 204 cN0 patients (including 47 pN2) underwent thoracotomy lobectomy between July 2000 and December 2009. Pre- and intraoperative status and postoperative survival between two groups were compared. Results There was no difference in preoperative conditions between two groups except Quantity of smoking. Operation time and blood loss of VATS group was significantly lower than thoracotomy group. Number of dissected lymph node (LN) stations was 3.3?+/-?1.1 in VATS group versus 3.3?+/-?1.3 in thoracotomy group, and the total number of LN was 12.7?+/-?8.9 in VATS group versus 10.5?+/-?7.2 in thoracotomy group. One- and 3-year disease-free survival rate was 82.6% in VATS group versus 72.0% in thoracotomy group, and 49.3% in VATS group versus 51.3% in thoracotomy group (P?=?0.996). One- and 3-year survival rate was 84.9% in VATS group versus 71.2% in thoracotomy group, and 64.0% in VATS group versus 42.7% in thoracotomy group (P?=?0.121). Conclusions VATS lobectomy is comparable with thoracotomy in both safety and curability for the treatment of cN0-pN2 NSCLC, without necessity of conversion to open surgery. J. Surg. Oncol. 2012; 106:431435. (c) 2012 Wiley Periodicals, Inc.

语种英语
WOS记录号WOS:000307550900013
引用统计
被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/68295
专题北京大学第二临床医学院_胸外科
作者单位Peking Univ, Dept Thorac Surg, Peoples Hosp, Beijing 100044, Peoples R China
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Li, Yun,Wang, Jung. Comparison of clinical outcomes for patients with clinical N0 and pathologic N2 non-small cell lung cancer after thoracoscopic lobectomy and open lobectomy: A retrospective analysis of 76 patients[J]. JOURNAL OF SURGICAL ONCOLOGY,2012,106(4):431-435.
APA Li, Yun,&Wang, Jung.(2012).Comparison of clinical outcomes for patients with clinical N0 and pathologic N2 non-small cell lung cancer after thoracoscopic lobectomy and open lobectomy: A retrospective analysis of 76 patients.JOURNAL OF SURGICAL ONCOLOGY,106(4),431-435.
MLA Li, Yun,et al."Comparison of clinical outcomes for patients with clinical N0 and pathologic N2 non-small cell lung cancer after thoracoscopic lobectomy and open lobectomy: A retrospective analysis of 76 patients".JOURNAL OF SURGICAL ONCOLOGY 106.4(2012):431-435.
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