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学科主题: 儿科学
题名:
不同病因矮身材儿童TW2-R、C、T骨龄评分特征研究
其他题名: Characteristics of R bone age, C bone age, and T bone age in children with different causes of short stature based on Tanner and Whitehouse skeletal age assessment system 2
作者: 崔蕴璞; 张铭涛; 王新利
关键词: 骨龄评估 ; 生长激素缺乏症 ; 特发性矮小 ; 小于胎龄儿 ; Turner综合征 ; 儿童 ; Bone age assessment ; Growth hormone deifciency ; Idiopathic short stature ; Small for gestational age ; Turner syndrome ; Child
刊名: 中国当代儿科杂志
发表日期: 2015
DOI: 10.7499/j.issn.1008-8830.2015.05.010
期: 5, 页:464-468
收录类别: 中国科技核心期刊 ; 中文核心期刊 ; CSCD
文章类型: Journal Article
摘要: 目的:探讨不同病因矮身材儿童TW2-R、C、T骨龄评分特征,为矮身材的病因诊断提供参考。方法以363例未经治疗的矮身材儿童为研究对象,根据病因分为4组:生长激素缺乏症(GHD,27例)、特发性矮小(ISS,280例)、小于胎龄儿(SGA,41例)、Turner综合征(TS,15例)。拍摄左手腕骨骨龄片,应用TW-2骨龄评分法对各组患儿R骨龄、C骨龄及T骨龄进行评分,将各序列骨龄与年龄对比分析。结果 GHD组男、女儿童表现为R骨龄、C骨龄及T骨龄均较年龄落后2岁以上。ISS组男童R骨龄、C骨龄及T骨龄较年龄落后约1岁;ISS组女童各序列骨龄与年龄比较无显著差异。SGA组男女儿童各序列骨龄与年龄比较无显著差异。TS组R骨龄及T骨龄较年龄显著落后,C骨龄与年龄比较无显著差异。结论不同病因所致的矮身材儿童具有不同的TW-2?R、C、T各序列骨龄特点。TW-2?R、C、T各序列骨龄的评估对于矮身材儿童病因的诊断具有辅助作用。 ObjectiveTo study the characteristics of R bone age, C bone age, and T bone age in children with different causes of short stature based on the Tanner and Whitehouse skeletal age assessment system 2 (TW2), and to provide a reference for the etiological diagnosis of short stature.MethodsThree hundred and sixty-three children with previously untreated short stature were classiifed into four groups according to the causes: growth hormone deifciency (GHD; 27 cases), idiopathic short stature (ISS; 280 cases), small for gestational age (SGA; 41 cases), and Turner syndrome (TS; 15 cases). The X-ray iflms of their left hand-wrist bones were taken to determine the bone age. R bone age, C bone age, and T bone age were assessed by the TW2 method and compared with their chronological age (CA). ResultsR bone age, C bone age, and T bone age were over 2 years less than CA in both boys and girls from the GHD group. In the ISS group, R bone age, C bone age, and T bone age were about 1 year less than CA in boys, while there were no significant differences between the bone ages and CA in girls. In the SGA group, there were no significant differences between the bone ages and CA in either boys or girls. In the TS group, R bone age and T bone age were signiifcantly lower than CA, while there was no signiifcant difference between C bone age and CA.ConclusionsThe children with different causes of short stature have different characteristics of R bone age, C bone age, and T bone age assessed by the TW2 method. The assessment of R bone age, C bone age, and T bone age by the TW2 method is helpful for the etiological diagnosis of short stature in children.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/69019
Appears in Collections:北京大学第三临床医学院_儿科_期刊论文

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作者单位: 北京大学第三医院儿科 北京 100191

Recommended Citation:
崔蕴璞,张铭涛,王新利. 不同病因矮身材儿童TW2-R、C、T骨龄评分特征研究[J]. 中国当代儿科杂志,2015(5):464-468.
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