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学科主题: 耳鼻咽喉科学
题名:
鼻息肉病中人类乳头状瘤病毒-DNA检测
其他题名: Human papillomavirus DNA test in nasal polypsis
作者: 周玉英; 胡牧; 刘翠苓
关键词: 鼻息肉病 ; 多聚酶链反应 ; 人类乳头状瘤病毒
刊名: 临床耳鼻咽喉科杂志
发表日期: 2001
DOI: 10.3969/j.issn.1001-1781.2001.05.008
卷: 15, 期:5, 页:212-213
文章类型: Journal Article
摘要: 目的:探讨鼻息肉病的病因。方法:对13例复发性鼻息肉的病理组织样本,用多聚酶链反应(PCR)进行人类乳头状瘤病毒(HPV)-DNA检测,10例正常鼻腔粘膜做对照。结果:13例鼻息肉第1次手术病理组织标本中有12例(92.3%)HPV-DNA感染,第2次手术有5例(38.5%)HPV-DNA感染,HPV分型发现以HPV6型最多,且以混和感染为主。10例正常鼻腔粘膜HPV阴性。结论:鼻息肉病可能与HPV 感染有一定关系。 Objective:To evaluate pathogenesis of nasal polypsis.Method:To detect HPV in 26 pathological samples of 13 cases by polymerase chain reaction(PCR).Ten cases of normal nasal mucous were used as control.Result:HPV-DNA was positive 12 cases(92.3%) in 13 cases of the first surgical operation by PCR.HPV-DNA was positive 5 cases(38.5%)in 13 cases of the second surgical operation by PCR.The most HPV type was HPV6.HPV-DNA was negative in 10 cases of control.Conclusion:The results showed that HPV plays an etiologic role in the development of nasal polypsis.
语种: 中文
原文出处: 查看原文
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内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/69224
Appears in Collections:北京大学第三临床医学院_耳鼻喉科_期刊论文

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作者单位: 1.北京大学第三医院耳鼻咽喉科
2.北京大学医学部病理系

Recommended Citation:
周玉英,胡牧,刘翠苓. 鼻息肉病中人类乳头状瘤病毒-DNA检测[J]. 临床耳鼻咽喉科杂志,2001,15(5):212-213.
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